HIV-infected women of Burkina Faso: a “reservoir” of mycoplasma infection

Djigma, Florencia Wendkuuni; Ouédraogo, C.M.R.; Sagna, T.; Ouermi, Djénèba; Sanogo, Korotini; Bisseyé, Cyrille; Kabre, Abdoulaye; Pietra, Virginio; Simporé, Jacques; Nikiema, Jean‐Baptiste; Musumeci, Salvatore

doi:10.3855/jidc.950

Cited by 11 publications

(15 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our study highlights the association of GBS vaginal colonization with HIV seropositivity. Although the association with HIV reported here might have been underestimated because HIV-positive status was based on history of tests carried out previous to this study, the finding is in agreement with the results of studies in Burkina Faso [17] and Zimbabwe [10], which also found a higher prevalence of GBS in pregnant women infected with HIV. However, such an association was not found in all previous studies [13,18].…”

Section: Discussionsupporting

confidence: 91%

Prevalence of colonization by Streptococcus agalactiae among pregnant women in Bukavu, Democratic Republic of the Congo

Mitima

Ntamako

Birindwa

et al. 2014

J Infect Dev Ctries

View full text Add to dashboard Cite

Introduction: Maternal vaginal colonization by Streptococcus agalactiae (GBS) has an important impact on neonatal health but has not been studied in the Democratic Republic of Congo. The aim of this study was to determine its frequency and influencing factors. Methodology: Vaginal samples (n = 509) for bacteriological analysis were collected from women in Bukavu, eastern DR Congo, during their third trimester of pregnancy, along with information about age, education and socio-economic status, and medical and obstetricgynecological history. Results: The overall GBS colonization rate was 20%. Colonization was significantly associated with low education, history of urinary infection during the pregnancy, history of premature childbirth or abortion, and HIV-positive serology, but was not significantly associated with socio-economic level or parity. Conclusions: The GBS colonization rate is similar to that found elsewhere on the continent. Further studies, with follow-up of neonates of infected mothers and evaluation of prevention/treatment strategies, are needed.

show abstract

Section: Discussionsupporting

confidence: 91%

Prevalence of colonization by Streptococcus agalactiae among pregnant women in Bukavu, Democratic Republic of the Congo

Mitima

Ntamako

Birindwa

et al. 2014

J Infect Dev Ctries

View full text Add to dashboard Cite

show abstract

“…in African women include studies of commercial sex workers in Kenya where the prevalence of M. genitalium was 13% and in Niger Republic where the prevalence of M. hominis was 37% (35, 36). Another study of M. hominis among HIV-positive women found a prevalence of 16.7% (37). Direct comparison of these results with ours is limited by differences in the study populations and method of characterizing Mycoplasma spp.…”

Section: Discussionmentioning

confidence: 99%

Mycoplasma hominis and Mycoplasma genitalium in the Vaginal Microbiota and Persistent High-Risk Human Papillomavirus Infection

Adebamowo

Zella

et al. 2017

Front. Public Health

View full text Add to dashboard Cite

BackgroundRecent studies have suggested that the vaginal microenvironment plays a role in persistence of high-risk human papillomavirus (hrHPV) infection and thus cervical carcinogenesis. Furthermore, it has been shown that some mycoplasmas are efficient methylators and may facilitate carcinogenesis through methylation of hrHPV and cervical somatic cells. We examined associations between prevalence and persistence of Mycoplasma spp. in the vaginal microbiota, and prevalent as well as persistent hrHPV infections.MethodsWe examined 194 Nigerian women who were tested for hrHPV infection using SPF25/LiPA10 and we identified Mycoplasma genitalium and Mycoplasma hominis in their vaginal microbiota established by sequencing the V3–V4 hypervariable regions of the 16S rRNA gene. We defined the prevalence of M. genitalium, M. hominis, and hrHPV based on positive result of baseline tests, while persistence was defined as positive results from two consecutive tests. We used exact logistic regression models to estimate associations between Mycoplasma spp. and hrHPV infections.ResultsThe mean (SD) age of the study participants was 38 (8) years, 71% were HIV positive, 30% M. genitalium positive, 45% M. hominis positive, and 40% hrHPV positive at baseline. At follow-up, 16% of the women remained positive for M. genitalium, 30% for M. hominis, and 31% for hrHPV. There was a significant association between persistent M. hominis and persistent hrHPV (OR 8.78, 95% CI 1.49–51.6, p 0.01). Women who were positive for HIV and had persistent M. hominis had threefold increase in the odds of having persistent hrHPV infection (OR 3.28, 95% CI 1.31–8.74, p 0.008), compared to women who were negative for both.ConclusionWe found significant association between persistent M. hominis in the vaginal microbiota and persistent hrHPV in this study, but we could not rule out reverse causation. Our findings need to be replicated in larger, longitudinal studies and if confirmed, could have important diagnostic and therapeutic implications.

show abstract

“…It is of interest to note from this review that all of 21 selected studies were published after the year (34). Moreover, there is a need for strong quality implementation of prevention of mother-to-child transmission programmes (16,18,19) and for this to contribute to WHO guidelines.…”

Section: Discussionmentioning

confidence: 99%

An assessment of HIV control programme for evidence informed policymaking and practice in Burkina Faso: A systematic review

Mèda

Chukwu

Hien

et al. 2019

Preprint

View full text Add to dashboard Cite

Background: Several studies have been undertaken on the subject of HIV. To improve the research findings into practices, stronger scientific evidences are suitable and have improved HIV control programmes in many countries including Burkina Faso. The objective of this study is to review the various HIV/AIDS researches related to HIV control programme in Burkina Faso and their implication for policy and practice. Methods: This study was a systematic review. A MEDLINE Entrez PubMed search was performed in August 2019 and implementation studies that investigated HIV control programmes and HIV health policy in Burkina Faso. Search key words included « HIV programmes in Burkina Faso », « HIV control programme in Burkina Faso », « Burkina Faso, health policy, HIV ». Only policy relevant studies which generated evidence to improve HIV control prgramme in Burkina Faso were eligible and were selected. Results: A total of 23 relevant studies that fulfilled the study inclusion criteria were identified out of 89 studies found. Among the 23 scientific publications included in the review, 73.9% were published in English language and 26.1% in French language. The main issues reviewed were related to prevention and other topics associated to prevention as an intervention on HIV control programme already operated in Burkina Faso, related to monitoring and evaluation to better control HIV programme. Others included studies were related to prevalence and risk factors, stigma, access to care to Non-gouvernmental-organizations-(NGO), access to and quality of care, gender, service delivery, priority setting and resource allocation. These studies generated high quality policy relevant evidence which indicated significant improvements in HIV programmes outcomes where the studies were undertaken Conclusion: There is a need for more implementation of research related to HIV in low income settings because of the priority to improve HIV outcomes and the challenge for implementing research and equity issues for interventions within complex health systems.

show abstract

HIV-infected women of Burkina Faso: a “reservoir” of mycoplasma infection

Cited by 11 publications

References 20 publications

Prevalence of colonization by Streptococcus agalactiae among pregnant women in Bukavu, Democratic Republic of the Congo

Prevalence of colonization by Streptococcus agalactiae among pregnant women in Bukavu, Democratic Republic of the Congo

Mycoplasma hominis and Mycoplasma genitalium in the Vaginal Microbiota and Persistent High-Risk Human Papillomavirus Infection

An assessment of HIV control programme for evidence informed policymaking and practice in Burkina Faso: A systematic review

Contact Info

Product

Resources

About