HIV Infection: What Should We Know?

Balatif, Ridwan

doi:10.32734/jetromi.v2i1.2038

Cited by 2 publications

(2 citation statements)

References 4 publications

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“…Persons infected with HIV are reluctant to report to the hospital on time, because of fear of experiencing discrimination and stigma from their community. This leads to treatment delay and progression of the disease, and eventually, resulting in acquired immunodeficiency syndrome (AIDS) stage, with the ability to develop an opportunistic infection [7]. With the inception of antiretroviral therapy (ART), HIV, which has been previously classified as a deadly disease, has now changed into a manageable chronic condition [8].…”

Section: Data Collectionmentioning

confidence: 99%

Paradoxical experiences of Ghanaian adolescents with HIV: physiological challenges

Doat¹,

Navab²,

Hoseini³

2021

HIV & AIDS Review

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Introduction: Adolescents living with human immunodeficiency virus (HIV) in sub-Saharan Africa continue to experience extreme health vulnerabilities. Children with HIV may experience major physiological problems. This study explored the experience of Ghanaian adolescents with HIV.Material and methods: Semi-structured interviews were used to collect data. 12 adolescents living with HIV between the ages of 14 to 19 years were recruited. Since a physiological problem is not without some level of emotional consequence, the most appropriate method to explore these physiological and emotional dimensions of treatment and diseases are through a qualitative research method.Results: Two main themes emerged from this study: 'Rhapsody of physiological burden' and 'Bittersweet experience of adjusting to antiretroviral therapy (ART)' . Participants reported experiencing challenges, including bouts of headaches, itchy skin rashes, general body weakness, vomiting, appetite loss, diarrhea, and many more. Adolescents reported varying accounts concerning ART. Some patients described positive image of treatment, while others reported traumatic ordeal regarding side effects of the treatment to the extent that some stopped taking their medications. Conclusions:Policies aimed at supporting adolescents living with HIV needs to consider their unique set of physiological challenges to help improve health outcomes of the youngsters. Nurses should inform patients about results as well as possible side effects of ART prior initiation of the regimen, and also explain adverse events, which should be reported to hospital.

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Section: Data Collectionmentioning

confidence: 99%

Paradoxical experiences of Ghanaian adolescents with HIV: physiological challenges

Doat¹,

Navab²,

Hoseini³

2021

HIV & AIDS Review

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“…HIV infection can disrupt various aspects, such as the economy, health, and education. 1 Various efforts have been made to overcome HIV infection, such as developing drugs to creating an HIV vaccine. Although HIV was discovered about 40 years ago, there has not been a single HIV vaccine approved in the broader community.…”

Section: Introductionmentioning

confidence: 99%

Recent Development on HIV Variants and HIV Vaccine

Balatif

Harahap

Almira

2022

Cermin Dunia Kedokteran

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Human immunodeficiency virus (HIV) is a virus from the Retrovirus family that attacks human immune cells, especially T lymphocytes. The increasing number of HIV cases requires a more effective preventive measure; among others is through vaccination. Although it has been about 40 years, there is no HIV vaccine on the market yet. It can be because of many variations of HIV and each country has its own dominant HIV variant. In addition, the ability of HIV virus to evade immune responses, high mutation rates, and limited experimental animals add to the difficulties to develop effective vaccines. As of May 2022, 16 vaccines are currently undergoing phase I/II clinical trials. Among HIV vaccines that have already undergone phase III clinical trials, only RV 144 vaccine gave promising results, with efficacy reaching 31.2%. The development of the HIV vaccine continues to obtain a safe and effective HIV vaccine. Human immunodeficiency virus (HIV) merupakan virus dari famili Retrovirus yang menyerang sel imun manusia terutama limfosit T. Kasus infeksi HIV yang terus meningkat, membutuhkan tindakan pencegahan yang lebih efektif antara lain dengan vaksin HIV. Tetapi, meskipun sudah sekitar 40 tahun, belum ada vaksin HIV yang diedarkan. Hal ini bisa karena banyaknya variasi HIV serta tiap negara memiliki varian HIV dominan yang berbeda. Selain itu, kemampuan HIV menghindari respon imun, laju mutasi yang tinggi, ditambah dengan keterbatasan hewan coba, menyulitkan pembuatan vaksin. Hingga bulan Mei 2022 terdapat 16 vaksin yang tengah menjalani uji klinis fase I/II. Di antara vaksin HIV yang sudah pernah menjalani uji klinis fase III, hanya vaksin RV 144 yang memberikan hasil menjanjikan yakni efikasi mencapai 31,2%. Perkembangan vaksin HIV terus berlanjut untuk mendapatkan vaksin HIV yang aman dan efektif.

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HIV Infection: What Should We Know?

Cited by 2 publications

References 4 publications

Paradoxical experiences of Ghanaian adolescents with HIV: physiological challenges

Paradoxical experiences of Ghanaian adolescents with HIV: physiological challenges

Recent Development on HIV Variants and HIV Vaccine

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