HIV risk behavior among men who have sex with men

Silan, Vijay; Kant, Shashi; Haldar, Partha; Goswami, Kiran; Sanjay, K; Misra, Puneet

doi:10.4103/1947-2714.118931

Cited by 9 publications

(7 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This study shows that socio-demographic characteristics and sexual behaviour of MSM correlate well with the other studies from India, done by Silan et al, Setia et al, Brahmam et al and Garg et al [10][11][12][13] The maximum number of MSM belonged to the age group 21 to 30 years; majority of them were unmarried, finished secondary level of school education and were employed as unskilled labourers.…”

Section: Discussionsupporting

confidence: 85%

Sexual risk behaviour and sexually transmitted infections in men who have sex with men

2020

View full text Add to dashboard Cite

Background: In India the estimated men who have sex with men (MSM) population is around 352, 000, among that 4.3% are living with HIV. The incidence of sexually transmitted infections (STIs) in MSM is greater than that reported in women and men who have sex with women only. The aim of the study is to determine the trends of sexual behaviour and the pattern of sexually transmitted infections in men who have sex with men.Methods: A retrospective study of the data collected from the clinical records of all MSM, who had attended the STI clinic of Kilpauk Medical College, Chennai, Tamil Nadu, during the three-year study period, from July 2016 to June 2019. Demographic data, sexual risk behaviour, condom usage and STIs, among the MSM, were computed and analyzed.Results: During the study period 489 MSM attended the STI clinic, 51.9% were bisexual and 48.1 % were homosexual. Among them, exclusive penetrative sex in 50.7%, exclusive receptive sex in 15.7% and both in 33.6% were reported. Condom usage was consistent in 18.8%, inconsistent in 28.8% and 52.9% never used condom. Unprotected sex is more common in oral sex than with anal sex. STIs were seen in 20.9% and HIV in 1.4% of MSM. Syphilis was the most common STI seen.Conclusions: Our study elucidated the high prevalence of STIs among MSM and increasing trends of sexual risk behaviour. Health service providers must take necessary steps to improve the provision of biological and medical measures to screen, treat and prevent infections.

show abstract

Section: Discussionsupporting

confidence: 85%

Sexual risk behaviour and sexually transmitted infections in men who have sex with men

2020

View full text Add to dashboard Cite

show abstract

“…MSM, especially those who practice RUAI, are known to be at particularly high risk for HIV-1 infection ( Silan et al, 2013 ). Our results show that high levels of MRJ-L in macrophages (41.5 fold) are as strong a risk factor as anal intercourse (43.9 fold) for HIV-1 acquisition.…”

Section: Discussionmentioning

confidence: 99%

Large Isoform of Mammalian Relative of DnaJ is a Major Determinant of Human Susceptibility to HIV-1 Infection

et al. 2014

View full text Add to dashboard Cite

SummaryIndividual differences in susceptibility to human immunodeficiency virus type 1 (HIV-1) infection have been of interest for decades. We aimed to determine the contribution of large isoform of Mammalian DnaJ (MRJ-L), a HIV-1 Vpr-interacting cellular protein, to this natural variation. Expression of MRJ-L in monocyte-derived macrophages was significantly higher in HIV-infected individuals (n = 31) than their uninfected counterparts (n = 27) (p = 0.009). Fifty male homosexual subjects (20 of them are HIV-1 positive) were further recruited to examine the association between MRJ-L levels and occurrence of HIV infection. Bayesian multiple logistic regression revealed that playing a receptive role and increased levels of MRJ-L in macrophages were two risk factors for HIV-1 infection. A 1% rise in MRJ-L expression was associated with a 1.13 fold (95% CrI 1.06–1.29) increase in odds of contracting HIV-1 infection. Ex vivo experiments revealed that MRJ-L facilitated Vpr-dependent nuclear localization of virus. Infection of macrophage-tropic strain is a critical step in HIV-1 transmission. MRJ-L is a critical factor in this process; hence, subjects with higher macrophage MRJ-L levels are more vulnerable to HIV-1 infection.

show abstract

“…In addition to college students, multiple epidemiologic studies have shown that binge drinking is highly prevalent among adult men who have sex with men (MSM) 3,4 …”

Section: Introductionmentioning

confidence: 99%

“…The college environment is one of unique emancipation, independence, and socialization, where alcohol use is common 2 . This is particularly true for SGM students, who are often exploring their identities and sexualities for the first time, increasingly identify outside of LGBT, and for whom substance use has been shown to be uniquely associated with sexual risk behavior, such as having sex under the influence of substances or condomless sexual behaviors, compared to their heterosexual peers 3,15 …”

Section: Introductionmentioning

confidence: 99%

Binge drinking and sexual risk behavior among US sexual and gender minority college students

Hyun

Stevens

et al. 2021

American J Addict

View full text Add to dashboard Cite

Background and Objectives Binge drinking and sexual risk behaviors have historically been associated with lesbian, gay, bisexual, and transgender (LGBT) adults; however, few studies have described this association among broader sexual and gender minority (SGM) students, who often identify outside of LGBT (e.g., asexual, queer). This study examined the relationship between binge drinking and sexual risk behaviors among SGM versus non‐SGM college students. Methods A retrospective analysis was conducted with cross‐sectional data from the Spring 2017 American College Health Association‐National College Health Assessment (ACHA‐NCHA) survey among US undergraduates (n = 47,821) across 92 institutions. Binge drinking was measured as more than five drinks consumed the last time the student socialized; sexual risk behavior was measured as the number of sexual partners in the past 12 months. Results Numerous undergraduates nationally identify as SGM (19.9%), with bisexual (32.7%), other SGM (26.1%), and asexual (25.4%) students comprising the largest subgroups. Prevalent among both SGM (28.1%) and non‐SGM (29.6%) students, binge drinking had a significant main effect on the number of sexual partners. A significant interaction effect was observed between SGM identity and binge drinking on the number of sexual partners, such that this association was stronger in SGM versus non‐SGM students. This effect remained significant across multiple SGM subgroups. Discussion and Conclusions SGM students are more prevalent and diverse than previously reported. While prevalent overall, binge drinking may be uniquely sexualized among SGM students. Scientific Significance In the first large‐scale study assessing drinking among disaggregated SGM college students, data suggest tailoring alcohol interventions to SGM students, particularly those identifying outside of LGBT.

show abstract

HIV risk behavior among men who have sex with men

Cited by 9 publications

References 7 publications

Sexual risk behaviour and sexually transmitted infections in men who have sex with men

Sexual risk behaviour and sexually transmitted infections in men who have sex with men

Large Isoform of Mammalian Relative of DnaJ is a Major Determinant of Human Susceptibility to HIV-1 Infection

Binge drinking and sexual risk behavior among US sexual and gender minority college students

Contact Info

Product

Resources

About