HLA antigen frequency in the Koya tribe of Andhra Pradesh, India

Abstract

The frequencies of HLA-A, -B, and -C antigens were studied in a tribal population of Koya from Andhra Pradesh in southern India. No other well-defined tribal population has been studied with which the present results may be compared. However, the HLA profile of Koya showed distinct differences from the general HLA distribution in India in the frequency of a large number of antigens both at the A and B loci. This study indicates the distinctiveness of this tribal population and suggests the potential importance of the study of HLA frequencies in tribal groups of India.

Distribution of HLA antigens in the native South Indian Tamil Hindus

“…Later regional studies on Indian population were also reported (Raha 1975, Bale et al 1980, Verma et al 1983). Recent works have covered selected endogamous groups including few castes and tribals (Papiha et al 1983, Pitchappan et al 1984, Rajashekar et al 1987, Selvakumar et al 1987. However, there is only one report (Mehra et al 1986) on the native Hindus in India that includes the Aryan Hindus of North India; this prompted us to undertake the present study to monitor the HLA distribution in the Tamil speaking South Indian Hindus.…”

HLA Antigens in Three Populations of India

“…During the last two decades, several in vestigations have established the HLA al lele frequency distributions in Indian im migrants living in Europe, Canada and Africa [Singal, 1972;Festenstein et a!., 1972;Brain and Hammond, 1972;Ham mond et al, 1975;Mittal et al, 1982], Re cently, HLA studies have been extended to several indigenous caste, tribal, and re gional groups of India [Bale et al, 1980;Wadia et al, 1980;Papiha et al, 1983;Verma et al, 1983;Pitchappan et al, 1984;Mehra et al, 1986: Rajashekar et al, 1987Selvakumar et al, 1987Selvakumar et al, , 1988. Consider ing the great diversity among the popula tions of the Indian region, these reports are just the beginning of the collection of the vital genetic information, required to understand the genetic variability and its maintenance, historical movements and the relationship among the populations.…”

Molecular diversity of HLA‐A*19 group of alleles in south Indian population

“…Few reports are also available on the immigrant Indian (Singal, 1972; Mittal et al ., 1982; Imanishi et al ., 1992) and regional Hindu population (Raha, 1975; Mittal et al ., 1982; Pitchappan et al ., 1984; Mehra et al ., 1986; Shankarkumar et al ., 1999). HLA studies on some endogamous groups, including a few castes and tribes in India, have also been published (Wadia et al ., 1980; Papiha et al ., 1983). However, considering the enormous diversity among the Indian population, the information available on the HLA is inadequate, and the data are rather scanty for the southern part of India.…”