Hochdifferenzierte Tumoren des Magen-Darm-Traktes mit argentaffinen und Panethschen Zellen

Hardmeier, T

doi:10.1007/bf00525159

Cited by 7 publications

(2 citation statements)

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“…Paneth cell-rich adenocarcinomas have been found in the stomach (Hardmeier 1966, Heitz 1980 It is very uncommon to find a differentiated epithelial tumour, such as a villous adenoma, in the small intestine and we would like to suggest that the study of the cellular composition and the histochemical characteristics of mucins of this tumour may provide information about the origin of the epithelial cells. In our study, all the four main cell types which are present in normal duodenal mucosa could be identified, as well as undifferentiated elements.…”

Section: Discussionmentioning

confidence: 98%

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Villous adenoma of the duodenum: cellular composition and histochemical findings

Mingazzini¹,

Malchiodi-Albedi²,

Blandamura³

1982

Histopathology

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A villous adenoma of the duodenum was studied histologically and histochemically by semi-thin sections using glycol-methacrylate as embedding medium. All the four epithelial cell types which are present in normal duodenal mucosa (absorptive columnar, goblet, Paneth, endocrine) were found in the tumour, as well as undifferentiated elements. Neutral and acid non-sulphated mucins were detected. Cell type distribution and mucin production varied according to the degree of differentiation. Foci of gastric metaplasia were observed. A possible histogenesis from crypt base stem cell is considered.

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Section: Discussionmentioning

confidence: 98%

“…Tumours of the gastrointestinal tract with a mixed cell population have previously been described in humans. Paneth cell-rich adenocarcinomas have been found in the stomach (Hardmeier 1966, Heitz 1980 Dawson 1979).…”

Section: Discussionmentioning

confidence: 99%