Homochiral Covalent Organic Frameworks for Asymmetric Catalysis

Abstract

Owing to their permanent porosity,h ighly ordered and extended structure, good chemical stability,a nd tunability,c ovalent organic frameworks (COFs) have emerged as a new type of organic materials that can offer various applications in different fields. Benefiting from the huge database of organic reactions, the required functionality of COFs can be readily achieved by modification of the correspondingo rganic functional groups on either polymerizable monomers or established COF frameworks. This striking feature allows homochiral covalent organic frameworks (HCCOFs) to be reasonably designed and synthesized, as well as their use as au nique platform to fabricate asymmetricc atalysts. This contribution provides an overview of new progress in HCCOF-based asymmetricc atalysis, including design, synthesis, and their application in asymmetric organic synthesis. Moreover, major challenges and developing trends in this field are also discussed. It is anticipatedt hat this review article will provide some new insights into HCCOFs for heterogeneousa symmetric catalysis and help to encourage further contributions in this young but promising field.

Heterostructured hybrids of metal–organic frameworks (MOFs) and covalent–organic frameworks (COFs)

“…10 Two-dimensional (2D) or 3D COFs consisting of accessible nanoscale channels or pores with uniform size and tunability have been widely prepared. 11 Their channel structures and pore walls provide a well-defined nanospace as reaction centers, thus leading to vast applications, such as in photocatalysis, 10,12 bioimaging and therapy, 13 electrochemical energy storage and conversion, 14 and electrocatalysis. 15…”

Covalent organic framework based multifunctional self-sanitizing face masks

“…45,47 Covalent organic frameworks (COFs) 48 with permanent porosity, highly ordered and extended structure, and tunable functionality have recently drawn intense attention due to their potential applications in catalysis, adsorption and separation, sensing, energy, and nanomedicine. [49][50][51][52][53][54][55][56][57][58][59][60] However, the most reported COFs with imine-linkages oen suffer from poor chemical stability under certain conditions. Recently, we and others developed a multicomponent reaction (MCR)-based methodology which is an alternative way to access COFs with robust linkages and multi-functionality by one-pot in situ polymerization.…”

Nanoscale covalent organic frameworks as theranostic platforms for oncotherapy: synthesis, functionalization, and applications

“…43,44 Due to the diversity of organic syntheses, COFs provide promising prospects for materials design, enabling function-and applicationoriented material syntheses. Until now, COFs have been widely used for separation and analysis, [45][46][47][48][49] heterogeneous catalysis, [50][51][52] sensing, 53 optoelectronics, 54 energy and environmental science, [55][56][57][58][59] and biomedicine. 60,61 In recent years, COFs, particularly nanoscale COFs (NCOFs), have joined a huge candidate library of biomedical nanomaterials because of their following unique features.…”