Homogeneous Catalytic Kinetics of Methyl Glycolate Hydrolysis

Abstract

Catalytic hydrolysis of methyl glycolate is a promising way to produce glycolic acid with high purity. The hydrolysis of methyl glycolate was investigated both in a stirred-batch reactor and in a reactive distillation column. Batch hydrolysis distillation was found to be rather effective in improving the conversion of methyl glycolate. A mechanism model including the cooperative catalysis of sulfuric acid and the generated glycolic acid was developed based on the acid-catalyzed hydrolysis mechanism and the protolysis equilibrium; then, the model was further simplified according to the relationship between the concentrations of hydroxonium ions and their providers. This simplified model could be easily introduced to Aspen Plus and applied to simulating the homogeneous hydrolysis process of methyl glycolate with or without sulfuric acid as catalyst via the reactive distillation technique.

Dealuminization for a Modified (Si–OH)n–Pt Interface: Self-Activation of Pt/NaY Catalysts for Oxidation of Ethylene Glycol in a Base-Free Medium

“…PGA and PLGA have been regarded as promising products for degradable plastics. − At present, the synthetic methods for GA include hydrolysis, cyaniding, carbonylation, and biological processes (as shown in Figure ). ,− However, these processes suffer from high operating pressure, severe equipment corrosion, or significant formation of toxic byproducts with poor GA yield . GA can also be obtained from coal conversion as an intermediate product.…”

Highly Active and Stable ZrO2 -SiO2 -Supported Cu-Catalysts for the Hydrogenation of Dimethyl Oxalate to Methyl Glycolate

“…Methyl glycolate (MG) is also known as hydroxy methyl acetate because of its molecules containing hydroxyl and esters that both belong to functional groups . It is an important organic raw material and a pharmaceutical intermediate and also has chemical properties of alcohols and esters, which can be a variety of chemical reactions carbonylation reaction, hydrolysis, and oxidation .…”

Synthesis of methyl glycolate by hydrogenation of dimethyl oxalate with a P modified Co/SiO2 catalyst

“…[1][2][3][4][5][6] It has been reported that MG can be hydrogenated to ethylene glycol (EG) and hydrolyzed to glycolic acid (an important raw material for the production of polyester fibres). [7][8][9] There are many ways to synthesize MG, such as carboxylation of formaldehyde, [10][11][12] coupling of formaldehyde and methyl formate, [13][14][15][16] selective hydrogenation of dimethyl oxalate (DMO), etc. [17][18][19][20] Among them, the hydrogenation of DMO to MG with high efficiency and environmentally friendly characteristics is recognized as the most promising one.…”

“…However, the hydrogenation of DMO to MG is also challenging because MG can subsequently be hydrogenated to ethylene glycol (EG) or ethanol and the thermodynamic constant of MG to EG is 2 orders of magnitude larger than that of DMO to MG, which makes the hydrogenation reaction hardly controlled in the first step. 7 Many studies have been conducted on this system. As far as we know, the reported catalysts in the DMO to MG system are mainly focused on Cu or Ag based catalysts, but the poor stability of Cu nanoparticles [21][22][23] and the high cost of noble metals (Ag) [24][25][26][27][28][29] makes their industrial application difficult.…”