Honey and Cardiovascular Risk Factors, in Normal Individuals and in Patients with Diabetes Mellitus or Dyslipidemia

Al-Waili, Noori S.; Salom, Khelod; Al-Ghamdi, Ahmad; Ansari, Mohammad Javed; Al-Waili, Ali N.; Al-Waili, Thia

doi:10.1089/jmf.2012.0285

Cited by 45 publications

(41 citation statements)

References 188 publications

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“…Mortality and morbidity due to cardiovascular disease are aggravated by a variety of risk factors, such as: minimal physical activity and exercise, smoking, poor dietary habits (diets high in fat and low in fiber), alcoholism, and others. (14,15) Several studies were developed to address the conditions of hypercholesterolemia and maintain cholesterol homeostasis. Cholesterol homeostasis is maintained via a complex arrangement in terms of absorption, anabolism, catabolism, and excretion.…”

Section: Discussionmentioning

confidence: 99%

“…The composition of the substances contained in honey is influenced by the type of crop, climate, and environmental conditions. (10,15,21) The hypotriglyceridemic effects of honey may be caused by fermented nondigestibleoligosaccharides (NDOs), such as fructooligosaccharides (FOS) or other similar carbohydrate isomaltulose which are contained in honey. Nondigestible-oligosaccarides (NDOs) are not hydrolyzed in the small intestine, but are degraded by microflora in the colon.…”

Section: Discussionmentioning

confidence: 99%

“…Honey contains several amino acid components. (15) According to Chen et al, (7) protein has the ability to lower of blood cholesterol and LDL cholesterol levels by inhibiting the reabsorption of bile acids, inhibiting HMG-CoA reductase and activating LDL receptors. In addition, honey also contains calcium.…”

Section: Discussionmentioning

confidence: 99%

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Honey improves lipid profile of diet-induced hypercholesterolemic rats

Nurmasitoh

Pramaningtyas

2016

UnivMed

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BACKGROUNDCoronary heart disease (CHD) is a major cause of morbidity and mortality throughout the world, including Indonesia. One of the risk factors for CHD is hypercholesterolemia. One of the natural products that has been developed for the treatment of hypercholesterolemia is honey. Honey contains fructooligosaccharides, various vitamins, minerals, and enzymes which are supposedly able to lower blood cholesterol levels. This research aimed to study the influence of honey on the levels of blood total cholesterol, triglyceride, and low density lipoprotein (LDL) levels in Wistar rats. METHODSThis study was of experimental post test control group design. Twentyfour male Wistar rats (Rattus norvegicus) were randomly divided into 4 groups. K1 was the negative control group (with normal diet), K2 was the positive control group (with high-fat diet), P1 was fed a high-fat diet for 7 days, followed by high-fat diet plus honey for the next 7 days. P2 was fed a high-fat diet for 7 days, followed by regular diet plus honey for the next 7 days. After completion of this treatment, total cholesterol, triglycerides, and LDL levels were measured by the cholesterol oxidase phenol+aminophenazone (CHOD-PAP) method using enzymatic spectrophotometry principles. RESULTSThere were significant differences in total cholesterol, triglyceride, and LDL levels between all groups after day 15 (p<0.05). CONCLUSIONHoney supplementation was able to reduce the blood levels of total cholesterol, triglycerides, and LDL. Honey supplementation accompanied by non-cholesterol feeds could more effectively lower total cholesterol, triglycerides, and LDL serum levels in Wistar rats. Keywords

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Honey improves lipid profile of diet-induced hypercholesterolemic rats

Nurmasitoh

Pramaningtyas

2016

UnivMed

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“…Several authors clinched that pure natural honey moderates cardiovascular (CVD) risk factors, predominantly in subjects with eminent risk and did not enhance body weight of obese subjects. [122,124] A study was conducted on humans for the post effects of taking 75 g of natural honey that was matched with equal amount of artificial honey. Rise in insulin and CRP level was ominously greater after the intake of glucose than after consumption of honey.…”

Section: Antioxidant Potentialmentioning

confidence: 99%

Phytochemistry, metabolism, and ethnomedical scenario of honey: A concurrent review

Ahmad

Hussain

Saeed

et al. 2017

International Journal of Food Properties

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Honey is a natural domestic sweet food material and a chemically diverse superfluous product of nectar acquired from flowers. Owing to the presence of higher amounts of antioxidant compounds covering phenolic, enzymes, organic acids, and bioactive peptides, it holds a strong ability to prevent various maladies. In addition, honey has also been exploited in certain cardiovascular, gastrointestinal, neoplastic, and inflammatory states along with its role in the treatment of copious infections and surgical wounds. Flavonoids and polyphenols are important bioactive components present in honey and have antioxidant properties. Some bioactive compounds, for example luteolin, galangin, isorhamnetin, quercetin, and kaempferol, are present in honey. Phenolic acids and flavonoids have important pharmacological activities such as anti-allergic, anti-biotic, anticarcinogenic, and hypoglycaemic. Moreover, curative potential of bioactive components and their utilisation in value added food products are also the limelight of this article. ARTICLE HISTORY

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“…In particular, these oligosaccharides may be responsible for the possible antidiabetic [34] and other health-related benefits of honey [1,34].…”

Section: (2)mentioning

confidence: 99%

The effect of a soy-yoghurt-honey product on excess weight and related health risk factors - A review

Koohkan¹,

McCarthy²,

Berg³

2017

JNHFS

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achieve this goal, supervised programs can be applied over a period of at least 6 months delivered by an interdisciplinary team of physicians, psychologists and group behavior consultants and nutritionists. This approach produces healthy modifications in diet and exercise for an individual's every day practice [10].Even if such a program is insufficient to prove the long-term success, the significant findings in obese adults confirms that using modified lifestyle interventions are at least comparable with the results of pharmacological interventions after 12-months [66]. Nevertheless, it is discouraging knowing the level of success in weight loss programs while only a very small number of obese patients can be motivated to participate in a lifestyle intervention program [25].There is agreement that long-term therapeutic lifestyle changes (TLC) such as dietary behavior reformations and increasing daily physical activity, are the cornerstones in the prevention and management of obesity and its related health risk factors and are often combined with cognitive behavior modification techniques [10,85]. Furthermore, the use of meal replacements has been accepted as an effective therapeutic strategy for weight loss, particularly in the beginning of an intervention [4,5,26,83,85].Dietary approaches can achieve as much weight loss in obese outpatients as has been reported for the most successful drug treatments, but compliance with the prescribed diet can be poor unless the dietary recommendations are simple to follow [73]. Moreover, weight loss interventions utilizing a meal replacement together with dietary counselling and increased physical activity have led to substantial and significant favorable reductions in anthropometric measurements and metabolic risk factors while preserving skeletal muscle mass [7,8]. T h e following review will specially focus on the efficiency of a clinically proven meal replacement product which is commercially available as a soy-yoghurt-honey formula (SYHF; Almased®) against overweight, obesity and its related health risks. AbstractThere is an agreement that long-term Therapeutic Lifestyle Changes (TLC) such as dietary behavior reformations and increasing daily physical activity, are the cornerstones in the prevention and management of obesity and its related health risk factors. Furthermore, the use of meal replacement diet has been accepted as an effective therapeutic strategy for a successful weight loss, particularly in the beginning of an intervention. The following review will specially focus on the efficiency of a clinically approved meal replacement product which is commercially available as a Soy-Yoghurt-Honey Formula (SYHF) which can be used to prevent, treat or manage overweight, obesity and its related health risks. The mentioned positive effects come not only by formula's low glycemic index as well as low caloric characteristics, but by its biologically active components such as soy isoflavones and soy and milk biological active peptides as well as antioxidants, enzymes and o...

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Honey and Cardiovascular Risk Factors, in Normal Individuals and in Patients with Diabetes Mellitus or Dyslipidemia

Cited by 45 publications

References 188 publications

Honey improves lipid profile of diet-induced hypercholesterolemic rats

Honey improves lipid profile of diet-induced hypercholesterolemic rats

Phytochemistry, metabolism, and ethnomedical scenario of honey: A concurrent review

The effect of a soy-yoghurt-honey product on excess weight and related health risk factors - A review

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