Background: Diabetic postmenopausal women and osteoporosis are both chronic conditions and the relationship between them are complex. Objective: The aims of this study were to assess the socio-demographic factors inflicted in Diabetic postmenopausal women with Osteoporosis condition. Method: A Prospective, comparative and interventional study with a convenient sample of 520 Diabetic postmenopausal subjects were recruited from both inpatient and outpatient: Orthopedic, General Medicine and Obstetrics and Gynecology departments in Malla Reddy Hospital, measuring Bone Mineral Density (BMD) at the heel bone using QUS. In addition, tabulated selfreported data forms, about the socio-demographic details of subjects were collected. Results: The QUS measurements at the culmination of the study deduced that 520 Diabetic postmenopausal women posed a high risk of anomalous BMD were 17% (n=89), whereas Low risk of anomalous BMD accounted for 61% (n=317) and No risk accounted for 22% (n=114), out of validated subjects. The socio-demographic and osteoporotic conditions were illustrated. There were significant differences in QUS-score (normal BMD, Osteopenia and osteoporosis) patient demographic details like current age, age at menopause, Menopausal duration, BMI, Occupation, Family history of osteoporosis, Family history of Fracture, Smoking habit, Alcohol habit, economic status, and education details were noted. Conclusion: The study emphasizes the prerequisites , namely risk factor identification and evaluation, strive for the decreased incidence of Osteoporosis. It also denotes the Health education programs to be an utmost desideratum amongst the population for Osteoporosis management.