Hormonal Therapy Is Associated With Better Self-esteem, Mood, and Quality of Life in Transsexuals

Gorin-Lazard, Audrey; Baumstarck, Karine; Boyer, Laurent; Maquigneau, A.; Penochet, Jean-Claude; Pringuey, D.; Albarel, F.; Morange, Isabelle; Bonierbale, M.; Lançon, Christophe; Auquier, Pascal

doi:10.1097/nmd.0000000000000046

Cited by 107 publications

(90 citation statements)

References 17 publications

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“…A meta-analysis on sex reassignment shows that CHT alone reduces GD and improves quality of life and psychological and psychosocial well-being (18). More recently, other studies have shown similar results, reporting that CHT is associated with a better quality of life (19,20), reduction of psychiatric comorbidity (15,21), lower social distress (21), less body dissatisfaction (4), and an improved sex life (14).…”

supporting

confidence: 55%

Cross-Sex Hormone Treatment and Psychobiological Changes in Transsexual Persons: Two-Year Follow-Up Data

Fisher¹,

Castellini²,

Ristori³

et al. 2016

The Journal of Clinical Endocrinology & Metabolism

169

143

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Context:To date, there are few studies investigating the impact of body changes induced by cross-sex hormonal treatment (CHT) on psychobiological well-being in gender-dysphoric persons (GDs). Objective:The objective of the study was to assess whether CHT-related body changes affect psychobiological well-being in GDs. Methods:A consecutive series of 359 GDs was considered for a cross-sectional section of the study. In addition, 54 GDs were studied in a 2-year follow-up. A physical examination was performed, including body mass index, waist circumference, and hair distribution. We also evaluated breast development and testis volume in male to female subjects and clitoris length in female to male. Subjects were asked to complete several psychometric measures for the assessment of body uneasiness, GD, and psychopathology levels. The evaluation was repeated 2 years prospectively. Results:The following results were found: 1) GDs undergoing CHT reported significantly lower subjective levels of GD, body uneasiness, and depressive symptoms as compared with those without; 2) CHT-induced body modifications were significantly associated with a better psychological adjustment; 3) during CHT, GDs reported a significant reduction of general psychopathology, depressive symptoms, and subjective GD, whereas social and legal indicators of GD showed a significant increase across time; and 4) among body changes induced by CHT, only breast development and increased body mass index had a significant impact on psychopathology reduction across time in male to female subjects and female to male subjects, respectively. Conclusions:The aforementioned results support the efficacy of CHT intervention in improving subjective perception of one's own body, which was partially associated with objective changes. (J Clin Endocrinol Metab 101: 0000 -0000, 2016)

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supporting

confidence: 55%

Cross-Sex Hormone Treatment and Psychobiological Changes in Transsexual Persons: Two-Year Follow-Up Data

Fisher¹,

Castellini²,

Ristori³

et al. 2016

The Journal of Clinical Endocrinology & Metabolism

169

143

View full text Add to dashboard Cite

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“…They verified that self-esteem interferes with both their perceptions of social support quality and their social support network size (Marshall et al, 2014). In this vein, knowing that the gender affirmation process enhances self-esteem, and that better self-esteem improves the social support network, the importance of providing hormonal therapy and surgical procedures becomes even more evident (Gorin-Lazard et al, 2013). …”

Section: Discussionmentioning

confidence: 99%

The Impact of the Parental Support on Risk Factors in the Process of Gender Affirmation of Transgender and Gender Diverse People

et al. 2018

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Research involving transgender and gender diverse people (TGD) increased in the last years, mostly concerning healthcare associated to this population. Few studies dedicated their analysis to the impact of parental support on transgender people, even though this is an important aspect in creating a safe environment on which these individuals can build their identity. In addition, the link between family support, TGD identity and homelessness is not completely established. Thus, due to the specificities of the family context of TGD individuals, the aim of this study is to investigate the association between family support and TGD in different moments of the process of gender affirmation. In addition, this study also aims to explore the relationship between a lack of social support and low self-esteem, home abandonment, and dwelling in the street. The survey was designed based on the TransPULSE project and was made available in electronic format. The sample was constituted of 423 TGD residents in two Brazilian states. A Structural Equation Model analysis suggested that the impact of gender affirmation status on homelessness was mediated by parental support, through self-esteem, and the need to move from home. The association between the status of the gender affirmation procedures, family support and self-esteem was significant and indicated that the further TGD individuals advanced in gender affirmation, the more self-esteem and family support they would have. The association between family support and self-esteem indicated that family support was associated with higher self-esteem. Low family support was associated with the willingness to move from home due to one’s TGD status and there was also a significant correlation between low self-esteem and the willingness to move from home due to one’s TGD status. Finally, homelessness was associated with the willingness to move with a large effect size. Limitations include the sample that was constituted by individuals with Internet access and who had more contact with TGD communities. The findings indicate directions for interventions involving TGD people and their families, considering the parental relationship as a critical variable to improve TGD quality of life in the process of gender affirmation.

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“…19 In another clinic-based study that recruited participants from psychiatric departments at teaching hospitals in France, the estimated prevalence of HT was 73%. 8 …”

Section: Discussionmentioning

confidence: 99%

Determinants of and Barriers to Hormonal and Surgical Treatment Receipt Among Transgender People

et al. 2016

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Purpose: Medical gender confirmation therapy (GCT) plays an important role in transgender health; however, its prevalence and determinants constitute an area of uncertainty.Methods: Data for this cross-sectional study were obtained from an online survey distributed from October 2012 through the end of 2013 among persons who visited the social media sites of a transgender education and social networking meeting. Eligible respondents (n=280) were persons whose gender identity was different from their sex assigned at birth and who responded to questions about previously received or planned hormonal therapy (HT), chest reconstruction, or genital surgery. Multivariable logistic regression models examined how receipt and plans to receive different GCT types were associated with participants' characteristics and gender identity.Results: The respective percentages of ever and current HT were 58% and 47% for transwomen and 63% and 57% for transmen. Genital surgery was reported by 11 participants; all transwomen. Relative to transmen, transwomen were thrice more likely to report plans to undergo genital surgery. By contrast, transmen were more than 10 times as likely as transwomen to have had or planned chest surgery. Older participants and those who were in a committed relationship were less likely to plan future GCT. Having health insurance was not associated with GCT receipt. Treatment cost was named as the main problem by 23% of transwomen and 29% of transmen. Accessing a qualified healthcare provider for transgender-related care was listed as the primary reason for not receiving surgery by 41% of transmen and 2% of transwomen.Conclusions: Prevalence of GCT differed across subgroups of participants and was lower than corresponding estimates reported elsewhere. The variability of results may reflect differences in recruitment procedures and response rates; however, it is also possible that it may be driven by geographic, socioeconomic, and health-related heterogeneity of the transgender population.

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Hormonal Therapy Is Associated With Better Self-esteem, Mood, and Quality of Life in Transsexuals

Cited by 107 publications

References 17 publications

Cross-Sex Hormone Treatment and Psychobiological Changes in Transsexual Persons: Two-Year Follow-Up Data

Cross-Sex Hormone Treatment and Psychobiological Changes in Transsexual Persons: Two-Year Follow-Up Data

The Impact of the Parental Support on Risk Factors in the Process of Gender Affirmation of Transgender and Gender Diverse People

Determinants of and Barriers to Hormonal and Surgical Treatment Receipt Among Transgender People

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