There are important limitations affecting product quality and human health during the production, processing, and consumption of seafood. Biogenic amines (BA), which are formed by microbial decarboxylation of amino acids in seafood, are important indicators of fillet quality due to their potential risks in food poisoning and bad odors (Yassoralipour et al., 2012). The importance of BAs for food is due to their potential toxicity when they are taken into the body more than the maximum intake specified in the Food and Drug Administration (FDA) and the codex and may result in headache, respiratory distress, heart palpitations, high or low blood pressure, and other allergic reactions. Not all BAs have the same toxic effect, and in general, it has been reported that histamine is the main cause of food poisoning, while potentials of the toxic effect of putrescine and cadaverine to other amines. In the literature, histamine poisoning levels are stated as follows for 100 g of fish: <5 mg histamine = safe, 5-10 mg histamine = possibly toxic, 20-100 mg histamine = probably toxic, >100 mg histamine = toxic (Özoğul & Özoğul, 2019).Although the legislation does not have an upper limit of BA levels in foods, there are some limits for histamine only, and there are mostly limitations on fishing products for this value. In the United States, the maximum allowable level for histamine in Scombroidtype fish is 50 mg/kg by FDA, 200 mg/kg by Codex Alimentarius, 100 mg/ kg by European Union regulations, 200 mg/kg by legal regulations in Germany, and 100 mg/kg by legal regulations in Canada, Finland, and Switzerland. In the Turkish Food Codex, the highest acceptable histamine value for fish is 200 mg/kg (Özoğul & Özoğul, 2019; Özdestan & Üren, 2012).