Hospital Center Merger in Europe Designed for Better Patient Care

Kendrick, Douglas B.

doi:10.1093/milmed/129.3.230

Cited by 2 publications

(1 citation statement)

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“…This period coincides with the significant increase in the number of medical procedures, such as blood transfusions and unsafe therapeutic injections, which are the main cause of the worldwide spread of HCV. 28 , 29 The plateau reached by the epidemic in the early 1990s seems to indicate the partial success of the new transfusion policies adopted in Turkey.…”

Section: Discussionmentioning

confidence: 99%

Healthcare-Related HCV Genotype 4d Infections in Kayseri, Turkey

Gökahmetoğlu

Polat

Atalay

et al. 2022

Turk J Gastroenterol

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Background: The frequency of genotype 4 hepatitis C virus infection is significantly higher in a city compared to other provinces in Turkey. In this study, we aimed to investigate the epidemiology and risk factors of hepatitis C virus genotype 4 infection in Kayseri province of Turkey. Methods: A case–control study was conducted with 61 hepatitis C virus genotype 4-infected patients and 71 controls. A questionnaire was administered to the patients and controls, asking for information about the risk factors of hepatitis C virus transmission. Core/E1 and NS5B regions of hepatitis C virus genome were amplified and sequenced by Sanger method. Phylogenetic analysis and molecular clock analysis were performed. The risk was determined by calculating the odds ratio and 95% CI. Logistic regression analysis was performed to determine the effect of risk factors by controlling for confounding variables. Results: Kayseri isolates were closely related to type 4d sequences but formed a separate cluster. According to the molecular clock analysis, hepatitis C virus genotype 4d entered Kayseri province probably between 1941 and 1988. Blood transfusion and surgical intervention were found to be significant risk factors for the infection. Conclusion: Epidemiological data showed that hepatitis C virus genotype 4d infections are significantly associated with unsafe medical procedures.

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Section: Discussionmentioning

confidence: 99%