Host Organisms: Algae

Specht, Elizabeth A.; Karunanithi, Prema S.; Gimpel, Javier; Ansari, William S.; Mayfield, Stephen P.

doi:10.1002/9783527807796.ch16

Cited by 8 publications

(6 citation statements)

References 201 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The term algae encompasses a wide range of photosynthetic organisms that are found primarily in freshwater and marine environments, although certain representatives can thrive in terrestrial niches, either on their own or by developing symbiotic relationships with other organisms [1,2]. Larger eukaryotic algae, such as seaweeds, are called macroalgae, while smaller unicellular eukaryotes are collectively referred to as microalgae.…”

Section: Introductionmentioning

confidence: 99%

“…Larger eukaryotic algae, such as seaweeds, are called macroalgae, while smaller unicellular eukaryotes are collectively referred to as microalgae. On the other hand, cyanobacteria (blue-green algae) represent the prokaryotic clade of this highly diverse group [2]. Moreover, some genera exhibit extraordinary growth potential in terms of produced biomass within a short period of time [3,4].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Algae and Their Metabolites as Potential Bio-Pesticides

Asimakis

Shehata²,

Eisenreich

et al. 2022

Microorganisms

View full text Add to dashboard Cite

An increasing human population necessitates more food production, yet current techniques in agriculture, such as chemical pesticide use, have negative impacts on the ecosystems and strong public opposition. Alternatives to synthetic pesticides should be safe for humans, the environment, and be sustainable. Extremely diverse ecological niches and millions of years of competition have shaped the genomes of algae to produce a myriad of substances that may serve humans in various biotechnological areas. Among the thousands of described algal species, only a small number have been investigated for valuable metabolites, yet these revealed the potential of algal metabolites as bio-pesticides. This review focuses on macroalgae and microalgae (including cyanobacteria) and their extracts or purified compounds, that have proven to be effective antibacterial, antiviral, antifungal, nematocides, insecticides, herbicides, and plant growth stimulants. Moreover, the mechanisms of action of the majority of these metabolites against plant pests are thoroughly discussed. The available information demonstrated herbicidal activities via inhibition of photosynthesis, antimicrobial activities via induction of plant defense responses, inhibition of quorum sensing and blocking virus entry, and insecticidal activities via neurotoxicity. The discovery of antimetabolites also seems to hold great potential as one recent example showed antimicrobial and herbicidal properties. Algae, especially microalgae, represent a vast untapped resource for discovering novel and safe biopesticide compounds.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Algae and Their Metabolites as Potential Bio-Pesticides

Asimakis

Shehata²,

Eisenreich

et al. 2022

Microorganisms

View full text Add to dashboard Cite

show abstract

“…Microalgae and cyanobacteria are part of a group of unicellular microorganisms found in aquatic and terrestrial environments, including fresh and sea water, they have the ability of growing photoautotrophically or heterotrophically, also have unique metabolic pathways for carotenoids, polyunsaturated fatty acids, proteins and polysaccharides production. Some of these compounds present antiviral activity that is further compared and detailed in Table 2 [70,71]. Algae are great hosts for the production of bioactive compounds, some of the most studied include: lectins, fucoidans, polysaccharides and proteins.…”

Section: Non-transgenic Microalgae-based Edible Polymers As Adjuvants...mentioning

confidence: 99%

Current challenges for modern vaccines and perspectives for novel treatment alternatives

Garduño-González

Peña-Benavides

Araújo

et al. 2022

Journal of Drug Delivery Science and Technology

View full text Add to dashboard Cite

“…Microalgae and cyanobacteria involve a diverse group of unicellular organisms found in aquatic (fresh- and sea-water) and terrestrial environments [ 8 ]. They are capable of growing either photoautotrophically or heterotrophically depending on the type of available carbon source; making their cultivation potentially simple and cost-effective [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

The Potential of Algal Biotechnology to Produce Antiviral Compounds and Biopharmaceuticals

et al. 2020

View full text Add to dashboard Cite

The emergence of the Coronavirus Disease 2019 (COVID-19) caused by the SARS-CoV-2 virus has led to an unprecedented pandemic, which demands urgent development of antiviral drugs and antibodies; as well as prophylactic approaches, namely vaccines. Algae biotechnology has much to offer in this scenario given the diversity of such organisms, which are a valuable source of antiviral and anti-inflammatory compounds that can also be used to produce vaccines and antibodies. Antivirals with possible activity against SARS-CoV-2 are summarized, based on previously reported activity against Coronaviruses or other enveloped or respiratory viruses. Moreover, the potential of algae-derived anti-inflammatory compounds to treat severe cases of COVID-19 is contemplated. The scenario of producing biopharmaceuticals in recombinant algae is presented and the cases of algae-made vaccines targeting viral diseases is highlighted as valuable references for the development of anti-SARS-CoV-2 vaccines. Successful cases in the production of functional antibodies are described. Perspectives on how specific algae species and genetic engineering techniques can be applied for the production of anti-viral compounds antibodies and vaccines against SARS-CoV-2 are provided.

show abstract

Host Organisms: Algae

Cited by 8 publications

References 201 publications

Algae and Their Metabolites as Potential Bio-Pesticides

Algae and Their Metabolites as Potential Bio-Pesticides

Current challenges for modern vaccines and perspectives for novel treatment alternatives

The Potential of Algal Biotechnology to Produce Antiviral Compounds and Biopharmaceuticals

Contact Info

Product

Resources

About