Hot flashes: emerging cardiovascular risk factors in recent and late postmenopause and their association with higher blood pressure

Abstract

In both phases, recent and late post menopause, hot flashes were associated with endothelial dysfunction and higher systolic and diastolic blood pressure, but the relationship between hot flashes and endothelial dysfunction was independent of blood pressure.

Association of vasomotor symptoms and sleep apnea risk in midlife women

“…Indeed, in a large population-based study involving 11,725 midlife women followed for 14 years, those reporting frequent VMS had an increased risk for incident CHD compared to those who did not, even after adjusting for multiple factors including age, menopausal status, lifestyle, BMI, diabetes and hypertension. 37 Reduced flow-mediated vasodilatation was also associated with VMS in recent (<10 years from last menstrual period) and late (>10 years from last menstrual period) postmenopause phases in one study, 38 but only among younger midlife women in another study. 20 In the Women’s Ischemia Syndrome Evaluation (WISE) study, women with early onset VMS (first occurring before the age of 42 years) had lower flow-mediated dilatation and higher cardiovascular mortality than those who experienced later onset VMS.…”

Menopausal hot flashes: The role of magnesium and select endocrine factors

“…Women with hot flashes may then be at risk for conditions related to vasospasm, but further investigation is needed. As mentioned earlier, hot flashes have been found to be associated with cardiovascular disease and dysfunction [57,58].…”

SLCO1B1 genetic variation and hormone therapy in menopausal women

“…This may ultimately contribute to better management of menopausal symptoms, improved quality of life, and potential mitigation of cardiovascular risk in menopausal women. 36 - 38 …”