This chapter explores the spillover effects of transnational mobility on professional and private life spheres, paying particular attention to the gender dynamics of vulnerability. From an interdisciplinary perspective, our aim is to explore the vulnerabilities associated with various forms of geographical mobility in societies (see Forbes-Mewett, 2020) characterised by increasing levels ofspatial displacement (Cresswell, 2006; Kaufmann, 2020) and by uneven shifts in gender norms across countries and among social groups (Bornatici et al., 2021; Daly, 2020; Esping-Andersen, 2009). We define transnational mobility as a physical displacement across borders that is imbued with a wide array of meanings, imaginaries and practices (Frello, 2008; Salazar & Smart, 2011). As a complex human experience, mobility is always entangled with other aspects of the life course (Cangià, 2021). Here, we are particularly interested in the interplay between the experience of transnational mobility, including different forms of short- or longterm cross-border relocation, and the gender configurations of professional and family life. Our empirical studies cover a diverse selection of geographically mobile and immobile people, including those who are commonly associated with privileged forms of transnational movement (Amit, 2011) and those who are often perceived as more constrained movers.