2018
DOI: 10.1038/d41586-018-02480-6
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How baby’s first microbes could be crucial to future health

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Cited by 49 publications
(24 citation statements)
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“…Postbiotics may be particularly useful in infants, as the first months of life are critical for developing the proper structure of the microbiota. As the microbiota "matures" up to about three years of age [1], any abnormalities can be associated with short-and long-term consequences (e.g., necrotizing enterocolitis and asthma, respectively) [105]. Creating the appropriate environment for the formation of the correct microbiota appears crucial for the proper development and preservation of the child's future well-being, and postbiotics can provide such conditions.…”
Section: Future Clinical Applicationsmentioning
confidence: 99%
“…Postbiotics may be particularly useful in infants, as the first months of life are critical for developing the proper structure of the microbiota. As the microbiota "matures" up to about three years of age [1], any abnormalities can be associated with short-and long-term consequences (e.g., necrotizing enterocolitis and asthma, respectively) [105]. Creating the appropriate environment for the formation of the correct microbiota appears crucial for the proper development and preservation of the child's future well-being, and postbiotics can provide such conditions.…”
Section: Future Clinical Applicationsmentioning
confidence: 99%
“…Estos microorganismos son capaces de establecerse en las barreras epiteliales del neonato dentro de los primeros cinco minutos de vida. 30 Al conjunto de estos microorganismos se le conoce como la primera microbiota neonatal y su composición fi logenética depende de la vía del nacimiento: 31,32 A través del parto natural, las bacterias que se establecen en las vías respiratorias altas, en el tracto gastrointestinal y en la piel del bebé, provienen del canal vaginal materno. Esta composición comprende a las bacterias grampositivas anaerobias, aerotolerantes, fermentadoras de lactato, del género Lactobacillus; y las bacterias gramnegativas anaerobias facultativas, no esporuladas, sacarolíticas y probióticas de los géneros Prevotella, Serratia, Bifidobacterium; y el fi lo Proteobacteria, que incluye a la familia de las Enterobacterias y algunas especies del grupo Bacteroidetes.…”
Section: Composición De La Microbiota En El Cuerpo Humanounclassified
“…Several factors are known to modulate the development of the infant microbiome, namely host genetics, prenatal environment, delivery mode and postnatal factors, such as antibiotics, environment or diet [3]. It is now known that the maturation of the human microbiome and its homeostasis with the human body might have longterm consequences for health [4].…”
Section: Introductionmentioning
confidence: 99%