How Does Maternal Diabetes Disrupt Embryonic and Fetal Development?

The composition of macro- and micronutrients in milk from six patients with tightly controlled insulin-dependent diabetes mellitus [median glycosylated hemoglobin concentrations at parturition of 5.2% (range 4.9-5.3%, reference range 4.9-6.6%) and 6 wk thereafter of 6.1% (range 5.0-6.3%, reference range 5.0-6.4%) was compared with that from five control subjects. Milk samples were collected halfway through a single breast-feeding at days 3-5 (colostrum); 7, 9, and 10 (transitional milk); and 12, 15, 17, 21, 25, 29, and 35 (mature milk). We found no abnormalities in macronutrient (triglycerides, lactose, and protein), cholesterol, glucose, and myoinositol concentrations or fatty acid composition. Two of three longitudinally studied patients showed rather constant ratios between glucose concentrations in milk and capillary blood. The present data suggest that tight control corrects a multitude of milk abnormalities associated with moderate and poor control.

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Breast-feeding and the diabetic mother

Whittaker

2001

British Journal of Midwifery

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This article aims to provide succinct information for midwives regarding the additional benefits afforded to diabetic women and their baby when breast-feeding. It can be acknowledged that such information is not currently readily available to the midwifery profession. Indeed, in 1995, a consultant psychiatrist, DF O'Sullivan, reported in the British Medical Journal that the British Diabetic Association was unable to provide sufficient information for his diabetic wife who was eager to breast-feed. This article will endeavour to depict the increased physiological and psychological benefits of breast-feeding for diabetic mothers and their babies.

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How Does Maternal Diabetes Disrupt Embryonic and Fetal Development?

Cited by 3 publications

References 64 publications

Hearing Screening Outcomes in Infants of Pregestational Diabetic Mothers

Hearing Screening Outcomes in Infants of Pregestational Diabetic Mothers

Milk of patients with tightly controlled insulin-dependent diabetes mellitus has normal macronutrient and fatty acid composition

Breast-feeding and the diabetic mother

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