Abstract. We have measured the isotopic abundances of neon and a number of other species in the galactic cosmic rays (GCRs) using the Cosmic Ray Isotope Spectrometer (CRIS) aboard the ACE spacecraft. Our data are compared to recent results from two-component (Wolf-Rayet material plus solar-like mixtures) Wolf-Rayet (WR) models. The three largest deviations of galactic cosmic ray isotope ratios from solar-system ratios predicted by these models, 12 C/ 16 O, 22 Ne/ 20 Ne, and 58 Fe/ 56 Fe, are very close to those observed. All of the isotopic ratios that we have measured are consistent with a GCR source consisting of ~20% of WR material mixed with ~80% material with solar-system composition. Since WR stars are evolutionary products of OB stars, and most OB stars exist in OB associations that form superbubbles, the good agreement of our data with WR models suggests that OB associations within superbubbles are the likely source of at least a substantial fraction of GCRs. In previous work it has been shown that the primary 59 Ni (which decays only by electron-capture) in GCRs has decayed, indicating a time interval between nucleosynthesis and acceleration of >10 5 yr. It has been suggested that in the OB association environment, ejecta from supernovae might be accelerated by the high velocity WR winds on a time scale that is short compared to the half-life of 59 Ni. Thus the 59 Ni might not have time to decay and this would cast doubt upon the OB association origin of cosmic rays. In this paper we suggest a scenario that should allow much of the 59 Ni to decay in the OB association environment and conclude that the hypothesis of the OB association origin of cosmic rays appears to be viable.