The present systematic review presents and analyzes several studies referred to the impact of social networks on the e-commerce of MSEs in the footwear sector, the general objective of our research is to determine the topics related to the impact of social networks on the e-commerce of MSEs in the footwear sector that have been elaborated during the last 10 years by researchers through a review and analysis of the selected articles. The databases used in the search for the studies used in the work are Scopus, SciELO, DOAJ and CORE; the inclusion and discard criteria of the work were chosen in order to be able to obtain studies that allow the elaboration of a precise, concrete and quality research, these articles must have been published within the years 2011-2021. In conclusion, it was identified that the topics related to the impact of social networks on the e-commerce of MSEs in the footwear sector that have been elaborated during the last 10 years by researchers are: "Social networks in companies", "Media", "Influence of consumers in social networks", "E-commerce in companies" and "Social networks and e-commerce". The limitations of this work were that the studies analyzed do not focus on digital instruments or tools for footwear ecommerce, new emerging means of payment in e-commerce, and consumer styles present in e-commerce.