How sweet is your love? Disentangling the role of marital status and quality on average glycemic levels among adults 50 years and older in the English Longitudinal Study of Ageing

Ford, Katherine J; Robitaille, Annie

doi:10.1136/bmjdrc-2022-003080

Cited by 11 publications

(6 citation statements)

References 37 publications

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“…Furthermore, a higher prevalence of diabetes mellitus type 2 was found among married participants in the present study. This is in disagreement with findings of previous studies where marriage was found to protect against type 2 diabetes mellitus [29]. Further study is needed to fully unravel the relationship between marital status and type 2 diabetes mellitus.…”

Section: Discussioncontrasting

confidence: 93%

Association of Undiagnosed Pre-Diabetes and Type-2 Diabetes Mellitus with Interleukin-2 mRNA Expression Among Adults in Bayelsa State, Nigeria

Ogbole,

Harold

2023

Int J Res Rev

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Many cases of hyperglycemia are undiagnosed in Nigeria due to poverty and inadequate access to health care. Although hyperglycemia and type 2 diabetes mellitus (T2DM) are inflammatory conditions, however, the role of inflammatory mediators such as interleukin-2 in hyperglycemia and T2DM is not fully understood. The aim of the present study was to evaluate the prevalence and association of undiagnosed pre-diabetes and T2DM with IL-2 mRNA level among adults in Bayelsa State, Nigeria. A cross sectional design was employed to randomly select 130 adults and they were grouped into three: normal control, prediabetes, and T2DM. Fasting blood glucose concentration was measured using Accu-answer glucometer, while mRNA level of IL-2 was quantified using real time PCR method. The prevalence of undiagnosed pre-diabetes was 43.07% (males, 19.23%; females, 23.85%) while undiagnosed T2DM was 16.15% (males, 6.92%; females 9.23%). The expression of IL-2 mRNA was significantly upregulated in both pre-diabetes and T2DM subjects compared with normal control (p < 0.05), but was significantly higher among T2DM subjects. Age ≥ 50 years, physical inactivity and marriage was significantly associated with hyperglycemia and T2DM (p < 0.05). The present study found a high prevalence of undiagnosed pre-diabetes and T2DM among adults in Bayelsa State, Nigeria. Association of prediabetes and T2DM with IL-2 mRNA expression was found. IL-2 mRNA level might be a useful biomarker for monitoring diabetes mellitus progression. Directing diabetes survey and interventions to rural communities is highly recommended. Keywords: [Undiagnosed Diabetes, pre-diabetes, IL-2, rural communities, Bayelsa State, Nigeria]

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Section: Discussioncontrasting

confidence: 93%

Association of Undiagnosed Pre-Diabetes and Type-2 Diabetes Mellitus with Interleukin-2 mRNA Expression Among Adults in Bayelsa State, Nigeria

Ogbole,

Harold

2023

Int J Res Rev

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“…Marital status appears to influence health behaviors and outcomes including glycemic control. Despite the small number of patients living without a partner in our study, similarly to other studies, [49] we found that they have higher A1C values compared to those who were married or living with a partner.…”

Section: Discussionsupporting

confidence: 86%

Health Literacy, Self-Efficacy and Glycemic Control in Patients With Diabetes Type 2 in a Greek Population

Panagiotidis,

Kalokairinou,

Tzavara

et al. 2024

Cureus

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To investigate the relationship between health literacy (HL), self-efficacy (SE), and achievement of treatment goals in patients with type 2 diabetes mellitus (T2DM). MethodThe cross-sectional study was conducted with a random sample of patients with T2DM attending the diabetology clinic and the Home Care department of the General Hospital of Drama, Greece. They completed two questionnaires: the short form of the European Health Literacy Survey Questionnaire (HLS-EU-Q16) to measure HL and the Diabetes Management Self-Efficacy Scale (DMSES) for people with T2DM to measure SE. Medical history, demographic characteristics, and values related to glycemic control were also recorded. Linear regression analysis was used to search for the dependence of glycosylated hemoglobin (A1C) values with HL and SE and the dependence between them. ResultAbout 120 patients with T2DM (response rate of 92.3%) were enrolled in the study. The mean age of the participants was 62.5 years [standard deviation (SD) = 10.6 years] and most of them were female (53.3%). A1C was found to be significantly negatively associated with diet, physical activity, and SE score. Also, a statistically significant positive correlation was found between HL and SE. HL was correlated with age, gender, education level, and A1C, with women and older people having lower HL, while conversely higher education level was significantly associated with higher HL. Higher A1C was significantly associated with lower HL. Also, SE partially mediates the relationship between HL and A1C, in a significant way. ConclusionThe results of the study confirm the important role of HL and SE in the successful management of T2DM. Multi-level educational interventions for diabetic patients could improve HL and SE and promote diabetes self-management.

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“…Conversely, living alone, rather than other forms of cohabitation, substantially increased the likelihood of experiencing multiple episodes of DKA (OR 2.7, 95% CI 1.09 to 6.66). It has been reported that being married is associated with lower HbA1c levels, 19 which may explain in part also a lowered risk of DKA, but data on marital status or cohabitation on DKA risk are lacking and our findings need further investigation.…”

Section: Discussionmentioning

confidence: 72%

Awareness and knowledge of diabetic ketoacidosis in people with type 1 diabetes: a cross-sectional, multicenter survey

Hepprich,

Roser,

Stiebitz

et al. 2023

BMJ Open Diab Res Care

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IntroductionTo evaluate awareness and knowledge of diabetic ketoacidosis (DKA), a common and potentially life-threatening complication in people living with type 1 diabetes (T1D).Research design and methodsA survey was developed to assess individuals’ current knowledge, management, and unmet needs regarding DKA. The study was conducted in six Swiss and three German endocrine outpatient clinics specialized in the treatment of diabetes.ResultsA total of 333 participants completed the questionnaire (45.7% female, mean age of 47 years, average duration of T1D at 22 years). Surprisingly, 32% of individuals were not familiar with the term ‘diabetic ketoacidosis’. Participants rated their own knowledge of DKA significantly lower than their physicians (p<0.0001). 46% of participants were unable to name a symptom of DKA, and 45% were unaware of its potential causes. 64% of participants did not test for ketones at all. A significant majority (67%) of individuals expressed the need for more information about DKA.ConclusionsIn patients treated in specialized centers, knowledge of DKA was found to be inadequate, with a lack of understanding regarding symptoms and causes. Healthcare professionals tended to overestimate individuals’ knowledge. Future efforts should focus on addressing these knowledge gaps and incorporating protective factors into the treatment of T1D.

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How sweet is your love? Disentangling the role of marital status and quality on average glycemic levels among adults 50 years and older in the English Longitudinal Study of Ageing

Cited by 11 publications

References 37 publications

Association of Undiagnosed Pre-Diabetes and Type-2 Diabetes Mellitus with Interleukin-2 mRNA Expression Among Adults in Bayelsa State, Nigeria

Association of Undiagnosed Pre-Diabetes and Type-2 Diabetes Mellitus with Interleukin-2 mRNA Expression Among Adults in Bayelsa State, Nigeria

Health Literacy, Self-Efficacy and Glycemic Control in Patients With Diabetes Type 2 in a Greek Population

Awareness and knowledge of diabetic ketoacidosis in people with type 1 diabetes: a cross-sectional, multicenter survey

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