How can the disintegration of ecosystems, the foundation of life on Earth, be halted and these critical systems be rehabilitated? For scholars, the action list is long: increase the pool of expertise by engaging all relevant knowledge communities, collect rapidly disappearing data, analyze with both familiar and new methods, and apply the results of actionable science to policy and practice. This enormously complex and urgent activity requires an integrated research framework with the flexibility to accommodate the global diversity of places, peoples, and processes and to examine future options. Based on evidence of environmental change and human activity, the framework termed historical ecology assembles tools to construct an evidence-validated, open-ended narrative of the evolution and transformation of specific ecosystems and landscapes. Welcoming knowledge from scholars and communities of both heritage and practice, this comprehensive and systemic understanding offers insights, models, and ideas for the durable future of contemporary landscapes. The article evaluates how practitioners could adjust aspects of practice and improve access to policy makers, and the discussion applies to regions and localities everywhere.