How to Reduce Resistance to Antibacterial Therapy?

The article provides data on the effectiveness of the use of the drug in the treatment of acute, chronic and recurrent diseases of the respiratory tract and ENT organs. The drug is an extract of Pelargonium sidoides. From the standpoint of modern pharmacology, it is known that the use of natural products based on plant materials ensures safety and the absence of pronounced side effects. The main active ingredients of pelargonium are phenolic compounds: coumarins, flavonoids and phenolic acids. The article details the biochemical and pharmacological properties of each of the above groups of compounds. It has been shown that the presence of several classes of phenolic compounds simultaneously contributes to the potentiation of the pharmacological effects of each group separately. Therefore, drug has a pronounced polytropic effect: antiviral, antibacterial, immunomodulatory, mucolytic, anti-inflammatory, antioxidant, cytoprotective. The article presents the results of numerous domestic and foreign randomized, placebo-controlled studies demonstrating its high efficacy and safety in the treatment of ENT diseases, upper respiratory tract infections and bronchitis, not only in adults, but also in children over 1 year old. On the basis of the analyzed and presented material, the authors concluded that the use of a natural-based drug in the treatment of acute respiratory infection is effective and safe, both as monotherapy and in combination with other medicinal substances. He is able to quickly eliminate not only the symptoms of inflammation, but also to support the body with any ailments of this type.

Modern possibilities of herbal medicine in the treatment of acute inflammatory diseases of the upper respiratory tract

Гуров

Muzhichkova

2021

Differential diagnosis and effective therapy for sore throat

Дербенева

2021

Sore throat is a common complaint, which can be caused by a typical viral pharyngitis, or it can be rooted in a life-threatening disease such as epiglottitis or inflammation of the cellular spaces in the throat and neck. The doctor should take a closer look at a patient with a sore throat, immediately make a differential diagnosis and prescribe adequate treatment, including surgical intervention, if necessary.The article discusses the most common causes of a sore throat, including various types of pharyngitis, paratonsillar abscess, parapharyngeal abscess, retropharyngeal abscess, epiglottitis.Viral pharyngitis has a favourable prognosis, resolves without intervention and complications, but bacterial and fungal pharyngitis have a more severe course. Streptococcal pharyngitis caused by group A в-hemolytic streptococcus holds a dominant position in bacterial etiology and requires the use of antibiotic therapy. The differential diagnosis of streptococcal pharyngitis is based on the modified Centor scores in the routine clinical practice. Antibiotic therapy for streptococcal pharyngitis includes a 10-day course of unprotected penicillins. If a patient has an allergic reaction to penicillins, it is recommended to use clindamycin or clarithromycin. The surgical intervention combined with intramuscular or intravenous antibiotic therapy is recommended for the treatment of purulent processes in the cellular spaces of the neck. These diseases can have life-threatening complications, which include neurological damage, the spread of purulent process in the mediastinum with the development of mediastinitis, laryn-geal stenosis, sepsis, necrotizing fasciitis, jugular vein thrombosis and erosion of the carotid artery. The third generation cephalosporins and protected penicillins are recommended for the treatment of epiglottitis, and respiratory fluoroquinolones are used, if a patient has a history of allergic reactions to penicillins. In severe cases with symptoms of stenosis, intubation can be performed in addition to the use of antibiotics.

Possibilities of phytotherapy in the treatment of acute respiratory infections in children

Холодова

2022

Self Cite

РезюмеВ статье обсуждается вопрос об особенностях течения и лечения острых респираторных инфекций у детей на современном этапе. Подчеркивается, что нерациональное использование антибиотикотерапии приводит к возрастаю щей антибиотикорезистентности, к развитию побочных эффектов. С целью улучшения эффективности терапии предлагается использование средств традиционной медицины, в частности фитотерапии. Фитотерапия -это научно обоснованное лечение лекарственными растениями или их частями, применяемое в нативной свежей или в высушенной форме, а также в виде галеновых препаратов. Данное лечение особенно целесообразно у чувствительных пациентов, у пациентов с коморбидными и полиморбидными состояниями, при наличии резистентности к показанным пациенту препаратам для предотвращения развития побочных явлений, на этапе реабилитации, а также с целью профилактики различных заболеваний. С целью лечения ОРИ и ее осложнений обосновывается использование в протоколах лечения фитотерапевтического препарата Умкалор.