How willing are you? Willingness as a predictor of change during treatment of adults with obsessive-compulsive disorder

Reid, Adam M.; Garner, Lauryn E.; Kirk, Nathaniel Van; Gironda, Christina; Krompinger, Jason W.; Brennan, Brian P.; Mathes, Brittany M.; Monaghan, Sadie Cole; Tifft, Eric D.; André, Marie-Christine; Cattie, Jordan E.; Crosby, Jesse M.; Elias, Jason A.

doi:10.1002/da.22672

Cited by 41 publications

(26 citation statements)

References 54 publications

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“…The task dimension of working alliance, which is how much the patient and therapist agree on what they should do in therapy, may be a possible mediator of the relationship between compliance and outcome (Hagen et al, 2016;Wheaton, Huppert, Foa, & Simpson, 2016). Lastly, more willingness to experience anxiety, obsessions and bodily sensations have also been related to more and faster symptom reduction during ERP (Reid et al, 2017).…”

Section: Psychological and Pharmacological Treatmentsmentioning

confidence: 97%

“…This can lead to an increase in distress, obsessional frequency, and low mood Purdon, Rowa, & Antony, 2005). In contrast, ERP and other forms of psychological treatment ask patients to systematically increase their anxiety during exposure, which in turn often leads to a higher tolerance of emotional distress and less need to neutralize or distract oneself from obsessions (Grøtte et al, 2015;Reid et al, 2017).…”

Section: Behavioralmentioning

confidence: 99%

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Effects of Bergen 4-Day Treatment on Resting-State Graph Features in Obsessive-Compulsive Disorder

Thorsen

Vriend

Wit

et al. 2021

Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

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It takes a village to raise a child and even more to raise a scientist, and this thesis would not be possible without years of work by my supervisors. I wish to thank Gerd Kvale and Bjarne Hansen for bothering to answer an email from me, a naïve psychology student, in November 2013. I had just received an offer to revise and resubmit my first article by a slightly confused editor who probably didn't understand what to do with a review paper written by a student with no supervisor. Gerd and Bjarne decided to give me a chance to work as a research assistant, which became the first building block of my PhD and our first paper together (Thorsen, van den Heuvel, Hansen, & Kvale, 2015). I wish to thank Bjarne and Gerd for showing how to combine being a caring person, clinician, and scientist. In addition, I thank them for trusting eager new students with important work and for guiding both patients and students to help them prosper. I wish to thank Odile van den Heuvel for her kind, intensive, generous, and enlightening guidance on how to combine living a good life and doing science. I remember travelling to Amsterdam for the first time in June 2014, then an eager and anxious 23-year old. However, my anxiety was soon lifted by Odile, the members of her research group, and her lovely family. I especially wish to thank her for her utmost generosity in inviting to me to live with her and her family for many of my visits to Amsterdam. Words cannot express my gratitude to my supervisors, and I look forward to working and spending time together in the future. I wish to thank my family and friends which make both life and work meaningful. I especially wish to thank Stella J. de Wit for guidance, discussions, and lots of fun throughout my PhD. I also thank her for inviting me to get to know her dear family. My visits to Weesp are very dear to me,

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Section: Psychological and Pharmacological Treatmentsmentioning

confidence: 97%

Section: Behavioralmentioning

confidence: 99%

Effects of Bergen 4-Day Treatment on Resting-State Graph Features in Obsessive-Compulsive Disorder

Thorsen

Vriend

Wit

et al. 2021

Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

View full text Add to dashboard Cite

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“…Therefore, these predictors should be validated in prospective controlled studies, focusing on long-term outcomes to build on the findings presented here. In addition, there may be other important predictors that were not included in this study, e.g., the therapeutic relationship [93], motivational processes [94][95][96], and patient adherence [97,98], childhood maltreatment [99], and expectations [100]. Future studies should routinely collect data on therapist variables (e.g., experience as indicated by years of training, level of competence as indicated by interpersonal skill set) and the therapeutic relationship using adequate measures.…”

Section: Future Research Directionsmentioning

confidence: 99%

Determining prognostic variables of treatment outcome in obsessive–compulsive disorder: effectiveness and its predictors in routine clinical care

Herzog

Osen

Stierle

et al. 2021

Eur Arch Psychiatry Clin Neurosci

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The objectives of this study were to investigate the naturalistic effectiveness of routine inpatient treatment for patients with obsessive–compulsive disorder (OCD) and to identify predictors of treatment outcome. A routinely collected data set of 1,596 OCD inpatients (M = 33.9 years, SD = 11.7; 60.4% female) having received evidence-based psychotherapy based on the cognitive–behavioral therapy (CBT) in five German psychotherapeutic clinics was analyzed. Effect sizes (Hedges' g) were calculated for several outcome variables to determine effectiveness. Predictor analyses were performed on a subsample (N = 514; M = 34.3 years, SD = 12.2; 60.3% female). For this purpose, the number of potential predictors was reduced using factor analysis, followed by multiple regression analysis to identify robust predictors. Effect sizes of various outcome variables could be classified as large (g = 1.34 of OCD–symptom change). Predictors of changes in OCD and depressive symptoms were symptom severity at admission and general psychopathological distress. In addition, patients with higher social support and more washing compulsions benefited more from treatment. Subgroup analyses showed a distinct predictor profile of changes in compulsions and obsessions. The results indicate that an evidence-based psychotherapy program for OCD can be effectively implemented in routine inpatient care. In addition to well-established predictors, social support, and washing compulsions in particular were identified as important positive predictors. Specific predictor profiles for changes in obsessions and compulsions are discussed.

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“…13 Willingness to experience unpleasant thoughts, emotions and bodily sensations in an open, accepting and nonjudgemental way appears to be a predictor of successful ERP. 14 Therefore, techniques that promote tolerance towards unpleasant thoughts and emotions may address the limitations of classical treatment. Particularly promising approaches for the reduction of symptom severity in OCD are mindfulness-based and acceptance-based programmes (MABPs) such as mindfulness-based stress reduction (MBSR), mindfulness-based cognitive therapy (MBCT), dialectical-behavioural therapy (DBT) and acceptance and commitment therapy (ACT).…”

Section: Open Accessmentioning

confidence: 99%

Mindfulness-based and acceptance-based programmes in the treatment of obsessive–compulsive disorder: a study protocol for a systematic review and meta-analysis

2021

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IntroductionCognitive–behavioural therapy (CBT) with exposure and response prevention is the recommended standard for the treatment of obsessive–compulsive disorder (OCD). However, a high proportion of patients refuse this treatment, do not respond or relapse shortly after treatment. Growing evidence suggests that mindfulness-based and acceptance-based programmes (MABPs) are an effective option for the treatment of OCD. This systematic review and meta-analysis will examine the effectiveness of MABPs in treating OCD. We also aimed to explore potential moderators of the programmes’ effectiveness.Methods and analysisWe will systematically search MEDLINE, Embase, PsycINFO, PSYINDEX, Web of Science, CINAHL and Cochrane Register of Controlled Trials (no language restrictions) for studies that evaluate the effect of MABPs on patients with OCD. We will conduct backward and forward citation searches of included studies and relevant reviews and contact corresponding authors. The primary outcome will be pre-post intervention change in symptom severity. A secondary outcome will be change in depressive symptoms. Two reviewers will independently screen the records, extract the data and rate the methodological quality of the studies. We will include both controlled and uncontrolled trials. Randomised controlled trials will be meta-analysed, separately assessing between-group effects. A second meta-analysis will assess the within-group effect of all eligible studies. We will explore moderators and sources of heterogeneity such as the specific programme, study design, changes in depressive symptoms, hours of guided treatment, control condition and prior therapy (eg, CBT) using metaregression and subgroup analyses. We will perform sensitivity analyses using follow-up data. A narrative synthesis will also be pursued. We will use the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system to assess the quality of the evidence.Ethics and disseminationEthical approval is not required. Results will be published in peer-reviewed journals and presented at international conferences.

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How willing are you? Willingness as a predictor of change during treatment of adults with obsessive-compulsive disorder

Abstract: Willingness to fully experience unpleasant and unwanted thoughts, emotions, and bodily sensations during exposures appears to be a marker of successful exposure therapy in adults with OCD. Future research should examine how willingness may enhance extinction learning during ERP.

Cited by 41 publications

References 54 publications

Effects of Bergen 4-Day Treatment on Resting-State Graph Features in Obsessive-Compulsive Disorder

Effects of Bergen 4-Day Treatment on Resting-State Graph Features in Obsessive-Compulsive Disorder

Determining prognostic variables of treatment outcome in obsessive–compulsive disorder: effectiveness and its predictors in routine clinical care

Mindfulness-based and acceptance-based programmes in the treatment of obsessive–compulsive disorder: a study protocol for a systematic review and meta-analysis

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