2015
DOI: 10.1007/s10600-015-1298-4
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HPLC Determination of Free and Bound Amino Acids in Bryonia alba

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Cited by 7 publications
(5 citation statements)
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“…This library largely consisted of plants with ethnopharmacological relevance that have previously been identified as a rich source of cyclotides such as Viola odorata , Viola tricolor , Psychotria solitudinum , Palicourea tomentosa and Carapichea ipecacuanha ( Koehbach et al, 2013 ; Fahradpour et al, 2017 ; de Veer et al, 2019 ). Furthermore, the plant extract library included species that are rich in other cyclotide-like or knottin peptides such as Bryonia alba , Beta vulgaris , Sambucus nigra as well as Momordica charantia ( He et al, 2013 ; Karpyuk et al, 2015 ; Álvarez et al, 2018 ; Retzl et al, 2020 ). Using solvent and solid phase extraction yielded the plant extracts enriched in cysteine-rich peptides.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…This library largely consisted of plants with ethnopharmacological relevance that have previously been identified as a rich source of cyclotides such as Viola odorata , Viola tricolor , Psychotria solitudinum , Palicourea tomentosa and Carapichea ipecacuanha ( Koehbach et al, 2013 ; Fahradpour et al, 2017 ; de Veer et al, 2019 ). Furthermore, the plant extract library included species that are rich in other cyclotide-like or knottin peptides such as Bryonia alba , Beta vulgaris , Sambucus nigra as well as Momordica charantia ( He et al, 2013 ; Karpyuk et al, 2015 ; Álvarez et al, 2018 ; Retzl et al, 2020 ). Using solvent and solid phase extraction yielded the plant extracts enriched in cysteine-rich peptides.…”
Section: Resultsmentioning
confidence: 99%
“…To this end, we established a library of plant extracts largely consisting of species with ethnopharmacological relevance that have previously been identified as a rich source of cyclotides or cyclotide-like knottin peptides. This encompasses ten plant species: Viola odorata , Viola tricolor , Psychotria solitudinum , Palicourea tomentosa , Carapichea ipecacuanha, Bryonia alba , Beta vulgaris , Sambucus nigra as well as Momordica charantia ( He et al, 2013 ; Koehbach et al, 2013 ; Karpyuk et al, 2015 ; Fahradpour et al, 2017 ; Álvarez et al, 2018 ; de Veer et al, 2019 ; Retzl et al, 2020 ). Using solvent and solid-phase extraction yielded the plant extracts enriched in peptides.…”
Section: Introductionmentioning
confidence: 99%
“…Besides cucurbitacins, which are the most significant compounds presented in B. alba extract, other compounds in the extract, such as lectins, flavonoids, and lipids, also act synergistically to increase the biological activity [44]. Previous studies showed the significance of cucurbitacins isolated from B. alba, particularly cucurbitacins B, D, E, I, and their derivatives, owing to their therapeutic effect or adjuvant management [45][46][47]. Cucurbitacins J, K, and L are found in significant amounts in the roots [41,48] and exert cytotoxic effects [41].…”
Section: Resultsmentioning
confidence: 99%
“…Traditional medicine states its use for antiinflammatory, antibacterial, laxative‐purgative and smooth muscle relaxant properties, that appear to be due to the content in active principles (especially cucurbitacins) . It is known as a toxic species, but despite this fact, recent scientific sources confirm its promising therapeutical potential …”
Section: Introductionmentioning
confidence: 99%
“…[11] It is known as a toxic species, [12] but despite this fact, recent scientific sources confirm its promising therapeutical potential. [1,13] There is little evidence about the content of flavonoids in this species, as most of the studies are focused on its content of cucurbitacins, that seem to be found mainly in roots. [11,14] Previous reports suggest the presence of saponarin, vitexin, isovitexin [15] and lutonarin [16] in the composition of the aerial parts of B. alba L. To the best of our knowledge, these are the only scientific reports on the flavonoid composition of this species.…”
Section: Introductionmentioning
confidence: 99%