Huge Angiomyolipoma of the Tongue

Bauer, Vladimir; Alerić, Zorica; Bujas, Tatjana

doi:10.1177/0194599811415805

Cited by 7 publications

(8 citation statements)

References 3 publications

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“…The present case was positive for CD-34 and SMA, focally positive for S-100 and was negative for HMB-45. Our results agree with positivity described for SMA and negativity for HMB-45 in other cases of oral AML [1,3,4]. Immunoreactivity for CD-34 is similar to the results of Nakabayashi et al [8], and focal positivity for S-100 was also reported in a case of oral angiomyolipoma by Alvarez et al [1].…”

Section: Discussionsupporting

confidence: 92%

“…Angiomyolipoma is extremely rare in the oral cavity. To our knowledge, only 18 cases of angiomyolipoma have been reported in oral cavity till now; 6 cases in lower and upper lips, 6 cases in tongue, 5 cases on the palate and 1 in cheek [4,7,8]. A well circumscribed mass with no invasion is the most common clinical appearance.…”

Section: Discussionmentioning

confidence: 98%

“…Among extrarenal sites of AML, liver is the second most common site. Hepatic angiomyolipoma in both positive HMB-45 immunoreactivity and association with tuberous sclerosis is similar to renal AML, but extrarenal lesions of other sites are usually not associated with tuberous sclerosis and do not show positive immunoreactivity for HBM-45 [3,4].…”

Section: Introductionmentioning

confidence: 95%

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Angiomyolipoma of the Oral Cavity: A Rare Case Report

Amanpour¹,

Zarei²,

Faryabi³

et al. 2019

JDMS

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Angiomyolipoma (AML) is a rare, benign tumor composed of thick-wall blood vessels, smooth muscle component and mature adispose tissue. Differentiation from other benign and malignant mesenchymal lesions of oral cavity depends on recognition of these three histologic components, and immunohistochemical (IHC) techniques are also helpful. This tumor arise from perivascular epithelioid cells (PEComas) and kidneys followed by liver are the main locations of this soft tissue tumor. AMLs are rarely found in oral cavity and few case reports of oral AML have been reported in the literature. We report the first case of concurrent occurrence of AML of the tongue and peripheral giant cell granuloma of the gingiva in a 59-year-old patient. Clinically it was presented as a painless nodular mass with a smooth surface on the dorsal of the tongue. Based on histopathologic features and IHC staining the diagnosis of oral AML was done. The other lesion was a small sessile mass in interdental papillae of the lower incisors and microscopic examination showed the histologic features of a peripheral giant cell granuloma. Concurrent occurrence of PGCG which is a reactive mucosal hyperplasia and AML in our patient, could show the probable role of local trauma in the pathogenesis of these lesions.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 95%

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Angiomyolipoma of the Oral Cavity: A Rare Case Report

Amanpour¹,

Zarei²,

Faryabi³

et al. 2019

JDMS

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“…Hamartoma is a focal malformation that resembles a benign neoplasm in that it is composed of tissue elements normally found in that tissue but grows in a disorderly fashion [ 3 ]. AML is defined histologically as a benign pleomorphic mesenchymal tumor consisting of three histologic components: mature adipocytes, interlacing fascicles of smooth muscle cells, and abnormal tortuous convoluted thick-walled blood vessels without an elastic layer [ 3 6 7 8 9 ]. This classical triad is necessary for a definitive diagnosis [ 7 ].…”

Section: Discussionmentioning

confidence: 99%

Angiomyolipoma of the Glabellar Region

Kim

Chung

Park

et al. 2017

Arch Craniofac Surg

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Angiomyolipomas are hamartomatous lesions consisting of smooth muscle bundles, thick-walled blood vessels, and mature adipocytes. They are usually found in the kidneys of tuberous sclerosis patients and more rarely in other organs, such as the liver, the oral cavity, the sinonasal tract, the heart, the large intestines, the lungs, and the skin. Cutaneous angiomyolipoma has shown to be very rare and generally occurs at the ends of the digits, the elbows, the ears, and the nose. Herein, we report the first documented case of angiomyolipoma of the glabellar region.

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“…Four cases of AMLs in the tongue have been described [2,[10][11][12]. So far, however, there has been no report on AMLs at the base of the tongue (Table 1).…”

Section: Discussionmentioning

confidence: 99%