Hughes-Stovin Syndrome and Massive Hemoptysis: A Management Challenge

Abstract

Hughes-Stovin syndrome is a very rare clinical entity characterized by pulmonary artery aneurysms and deep vein thrombosis (DVT). Here we report the case of a 53-year-old man, admitted to Sultan Qaboos University Hospital, Muscat, Oman, with bilateral pulmonary artery aneurysms and lower-limb DVT who developed massive hemoptysis. He was managed successfully with high-dose steroids in combination with cyclophosphamide.

A Rare but Fatal Behçet Variant: The Hughes–Stovin Syndrome—Successful Case Report and New Evidence from Literature Review

“…A total of 40 patients were analyzed. 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 The comparison of surgical/medical or medical alone therapy on length of follow-up is reported in Fig 3 . No differences in survival rate were observed between the two groups.…”

Recurrent Haemoptysis Revealing Hughes-Stovin Syndrome

“…This theory was supported by findings of dilated and distorted bronchial arteries and convoluted small branches in digital subtraction angiograms. In addition, the pulmonary artery thrombosis develops in situ due to inflammation of the arterial wall and not as thromboembolism developing from peripheral vein thrombosis [7] .…”

Recurrent Haemoptysis Revealing Hughes-Stovin Syndrome

“…This theory was supported by findings of dilated and distorted bronchial arteries and convoluted small branches in digital subtraction angiograms. In addition, the pulmonary artery thrombosis develops in situ due to inflammation of the arterial wall and not as thromboembolism developing from peripheral vein thrombosis [7] . According to current opinion, HSS is caused by a vasculitis similar to that implicated in BD.…”

“…In cases of a high risk of major bleeding, embolization should be preferred to open surgery. This procedure is less invasive, enabling selective treatment of multiple bilateral aneurysms [7,10] . Despite the pro-thrombotic tendency and the risk of pulmonary embolism, the need for anticoagulation is not always clear.…”