INTRODUCTION: In the online English learning platform, noise interference makes people unable to hear the content of English teaching clearly, which leads to a great reduction in the efficiency of English learning. In order to improve the voice quality of online English learning platform, the speech enhancement method of the online English learning platform based on deep neural network is studied.OBJECTIVES: This paper proposes a deep neural network-based speech enhancement method for online English learning platform in order to obtain more desirable results in the application of speech quality optimization.METHODS: The optimized VMD (Variable Modal Decomposition) algorithm is combined with the Moth-flame optimization algorithm to find the optimal solution to obtain the optimal value of the decomposition mode number and the penalty factor of the variational modal decomposition algorithm, and then the optimized variational modal decomposition algorithm is used to filter the noise information in the speech signal; Through the network speech enhancement method based on deep neural network learning, the denoised speech signal is taken as the enhancement target to achieve speech enhancement.RESULTS: The research results show that the method not only has significant denoising ability for speech signal, but also after this method is used, PESQ value of speech quality perception evaluation of speech signal is greater than 4.0dB, the spectral features are prominent, and the speech quality is improved.CONCLUSION: Through experiments from three perspectives: speech signal denoising, speech quality enhancement and speech spectrum information, the usability of the method in this paper is confirmed.