Human chorionic gonadotropin in pregnancy diagnostics

Performance of a quick pregnancy test on whole blood in early pregnancy units: a prospective cohort study

“…The patient who had a negative NG-Test hCG WB and a serum hCG level of 35 UI/l had a residual hCG level after early pregnancy loss, which returned a negative result 48 h later. Intact hCG is the bioactive form produced by the syncytiotrophoblast and it accounts for the quasitotality of serum hCG in the first trimester [7][8][9]. The β unit is a metabolite arising from its degradation and disappears after intact hCG [9], explaining our falsenegative result.…”

Detection of unrecognized pregnancy prior to a fluoroscopy‐guided interventional procedure: A case report

“…Sensitivity and specificity of urine hCG are found to be 99% and 92.2%, respectively. Although the test could result false positive or false negative, such outcomes are infrequent and can easily be corrected by serum tests …”

Alphalisa for the Determination of Median Levels of the Free Β Subunit of Human Chorionic Gonadotropin in the Serum of Pregnant Women

“…The concentration subsequently decreases to a stable level. [2,3] The free b subunit of hCG (free b-hCG) is the sole serum biomarker that can be tested in first-and second-trimester screening. [4] It has been reported [5] that the level of free b-hCG in maternal serum in Downsyndrome pregnancies during the second trimester is at least twice as high as that of chromosomally normal pregnancies, whereas the level of free b-hCG is lower in fetal trisomy 18 and trisomy 13.…”