Human immunodeficiency virus type 2 infection in children

Faye, Albert; Burgard, Marianne; Crosnier, H.; Retbi, Jean-Marc; Blanche, Stéphane

doi:10.1016/s0022-3476(97)70290-7

Cited by 9 publications

(2 citation statements)

References 25 publications

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“…The first was maternal primary infection in late pregnancy, during a period when mother-to-child transmission prevention was not yet available. In a previous study of HIV-2-infected children in France [30], including this child and 2 others born in Africa, primary infection was involved in at least 2 cases. The second case of mother-to-child transmission was likely to have been Table 2 Figure 1).…”

Section: Discussionmentioning

confidence: 82%

Mother‐to‐Child Transmission of HIV‐2 Infection from 1986 to 2007 in the ANRS French Perinatal Cohort EPF‐CO1

Burgard¹,

Jasseron

Matheron

et al. 2010

CLIN INFECT DIS

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Section: Discussionmentioning

confidence: 82%

Mother‐to‐Child Transmission of HIV‐2 Infection from 1986 to 2007 in the ANRS French Perinatal Cohort EPF‐CO1

Burgard¹,

Jasseron

Matheron

et al. 2010

CLIN INFECT DIS

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“…1 However, the mother-to-child transmission rate of HIV-2 is reduced about 10-to 20-fold compared to HIV-1. 2,3 Vertical transmission of HIV-2 has been molecularly proved only once. 4 Compared to HIV-1, the epidemiology of HIV-2 is more difficult to study because most infections are diagnosed many years after infection has occurred.…”

mentioning

confidence: 99%

Phylogenetic Demonstration of Two Cases of Perinatal Human Immunodeficiency Virus Type 2 Infection Diagnosed in Adulthood

Barroso

Araújo²,

Gomes³

et al. 2004

AIDS Research and Human Retroviruses

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HIV-2 infection was diagnosed in two patients 15 and 24 years of age and, thereafter, in their mothers. Epidemiological data suggested that vertical transmission was the most probable mode of infection in both patients (Mota-Miranda A, et al.: AIDS 2001;15:2460-2461). Phylogenetic analysis of env C2-C3 sequences from the patients and their mothers was used in an attempt to confirm or exclude the events of perinatal HIV-2 transmission. Sequences from each putative transmission pair formed monophyletic clusters in phylogenetic analysis, a clear indication of common ancestry. Interpatient nucleotide distances increased with the period of infection being consistent with long-term infection. In conclusion, the results are consistent with an epidemiological linkage between the viruses infecting each mother-child pair and support the occurrence of perinatal HIV-2 infection in both cases. Application of similar phylogeny methods to other suspected transmission cases may permit a better understanding of the epidemiology and molecular evolution of HIV-2.

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Pediatric AIDS

Pediatric Allergy, Asthma and Immunology

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Human immunodeficiency virus type 2 infection in children

Cited by 9 publications

References 25 publications

Mother‐to‐Child Transmission of HIV‐2 Infection from 1986 to 2007 in the ANRS French Perinatal Cohort EPF‐CO1

Mother‐to‐Child Transmission of HIV‐2 Infection from 1986 to 2007 in the ANRS French Perinatal Cohort EPF‐CO1

Phylogenetic Demonstration of Two Cases of Perinatal Human Immunodeficiency Virus Type 2 Infection Diagnosed in Adulthood

Pediatric AIDS

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