Human infectious diseases and risk of preeclampsia: an updated review of the literature

Shiadeh, Malihe Nourollahpour; Moghadam, Zahra Behboodi; Adam, Ishag; Saber, Vafa; Bagheri, Maryam; Rostami, Ali

doi:10.1007/s15010-017-1031-2

Cited by 59 publications

(39 citation statements)

References 125 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The infection is usually asymptomatic or produces only mild symptoms. Severe complications can occur in certain groups: encephalitis, brain abscesses and death in immunocompromised individuals [13,14], pre-eclampsia, psychiatric disorders, abortion and foetal abnormality in pregnant women [15,16,17], and behavioural changes, neuropsychiatric disorders, and infertility in healthy humans and animals [18,19,20,21,22].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of <i>Toxoplasma gondii</i> antibodies in wild boar (Sus scrofa) from Strzałowo Forest Division, Warmia and Mazury Region, Poland

Puchalska¹,

Pyziel²,

Wisniewski³

et al. 2021

Ann Agric Environ Med.

View full text Add to dashboard Cite

Introduction and objective. Toxoplasmosis is an important zoonosis caused by a protozoan, Toxoplasma gondii. Raw or undercooked venison may be a source of infection in humans. The aim of the study was to determine the prevalence of T. gondii antibodies in wild boar from the Strzałowo Forest Division of the Warmia and Mazury Region of Poland. Materials and method. A total of 90 samples were collected from 50 wild boar: 40 from both tongue and diaphragm muscles, 4 from diaphragm muscles and six from tongue muscles. Samples were analyzed using the commercial PrioCHECK® Toxoplasma Ab porcine ELISA, according to the manufacturer's instructions. Results. T. gondii antibodies were detected in 24 of 50 (48%) tested animals. T. gondii antibodies were detected in 40 of 90 (44.4%) tested samples (21 of tongue muscles and 19 of diaphragm muscles). In the 40 wild boar that provided samples of meat juice from the tongue and diaphragm muscles, specific antibodies were more prevalent in the tongue (20 of 40 animals-50%) than in the diaphragm muscles (17 of 40 animals-42.5%). Conclusions. The study revealed a high percentage of wild boar seropositive to T. gondii. Muscle samples to obtain meat juice are easily available and simple to collect, even on the hunting grounds, which makes them suitable material for detecting T. gondii antibodies in wild boar. Wild boar are essential to T. gondii circulation in the environment, and raw or undercooked venison may be a source of human infections with this parasite.

show abstract

Section: Introductionmentioning

confidence: 99%

Prevalence of <i>Toxoplasma gondii</i> antibodies in wild boar (Sus scrofa) from Strzałowo Forest Division, Warmia and Mazury Region, Poland

Puchalska¹,

Pyziel²,

Wisniewski³

et al. 2021

Ann Agric Environ Med.

View full text Add to dashboard Cite

show abstract

“…Extremely significant similarities between the oral cavity microorganisms and the placenta were found [30]. On the other hand, inflammatory mediators, prooxidative factors, endo-and exotoxins and soluble forms of the adhesion molecules, which induce inflammation of the uteroplacental area, hypoxia, oxidative stress, endothelial dysfunctions leading to PE, penetrate into the cardiovascular bed as a result of periodontal inflammation [31].…”

Section: Discussionmentioning

confidence: 99%

Periodontitis and risk for preeclampsia — a systematic review

Konopka

2020

Ginekol Pol

View full text Add to dashboard Cite

Objectives: The aim of the study is to review systematic cohort and randomized trials on the relationship between periodontitis and preeclampsia. Periodontitis is an independent risk factor for preeclampsia (PE), and periodontal treatment could play a significant role in the prevention of this pregnancy complication. Material and methods: A total of 821 items (published until March 2019), thematically related to the relationship between periodontitis, its treatment and the incidence of preeclampsia, were collected from the databases of PubMed, Scopus, Google Scholar and the Polish Database of Medical Bibliography and analyzed. In the end, 6 cohort studies and 3 randomized controlled trials (from the years 2003-2016) were deemed eligible for the review. The main exclusion criteria were as follows: case-control and cross-sectional studies, medical and dental conditions. Results: A significant relationship between periodontitis and the risk for developing preeclampsia was demonstrated in 5 cohort trials, which was not confirmed by only 1 study. A total of 2724 pregnant women, including 195 (7.16%) with PE, were analyzed. In 3 randomized trials which assessed the impact of non-surgical treatment (scaling and root planing = SRP) on the occurrence of preeclampsia, the preventive effects of the implemented treatment was not confirmed. A total of 116 women from the group of 1825 pregnant subjects undergoing the non-surgical treatment (SRP) and 116 women from the control group of 1827 pregnant women were subsequently diagnosed with PE, which amounted to 6.30% and 6.35%, respectively. Conclusions: The cohort studies indicated that periodontitis may result in an increased risk for developing PE. A more detailed analysis regarding the impact of potential risk factors and modification of further studies (clarification of how periodontitis and preeclampsia should be defined in observations, consideration of disease severity, earlier at 12-16 weeks of gestation-implementation of the non-surgical treatment, modification and extension of the classical protocol of the non-surgical treatment of periodontal diseases, as well as conducting European studies), are necessary due to considerable discrepancies in the available literature sources (cohort and randomized observations).

show abstract

“…Some specific infections found to be associated with the development of pre-eclampsia include Chlamydia trachomatis ,16 Helicobacter pylori ,18 Chlamydia pneumoniae ,17 19 urinary tract infections,20 21 infection associated with periodontal disease,9 cytomegalovirus,10 and parasitic infections including Plasmodium spp and Toxoplasma gondii 10…”

Section: Discussionmentioning

confidence: 99%

Hsv Infection is Associated with Gestational Hypertension: Results from the Us National Inpatient Sample

Shi¹,

Wu²

2018

Journal of Investigative Medicine

View full text Add to dashboard Cite

The purpose of this study was to determine if there is an association between maternal herpes simplex virus (HSV) infection and pre-eclampsia/eclampsia or gestational hypertension. The US Nationwide Inpatient Sample database was searched for women aged 15-44 years who delivered in a hospital between 2005 and 2014. The patients were categorized into those with and without HSV and pre-eclampsia/eclampsia and gestational hypertension were compared between the groups. The analytic sample size (n=8 264 076) was equivalent to a population-based sample size of 40 653 030 patients. After adjusting for significant variables including age, race, income, insurance status, diabetes mellitus (DM), gestational DM, obesity, and multiple gestations, multivariate regression analysis indicated that HSV was associated with a higher OR for gestational hypertension (adjusted OR 1.038; 95% CI 1.004 to 1.072). However, HSV was not associated with pre-eclampsia/eclampsia (OR 1.001; 95% CI 0.968 to 1.035) in univariate regression analysis. The results of the current study suggest that HSV infection is associated with gestational hypertension but not pre-eclampsia. Given the prevalence of HSV infection and its potential association with hypertensive disorders of pregnancy, further study of HSV and hypertension in pregnancy is warranted.

show abstract

Human infectious diseases and risk of preeclampsia: an updated review of the literature

Abstract: Thus, early diagnosis and treatment of bacterial, viral, and parasitic infections could be an effective strategy to reduce the incidence of PE.

Cited by 59 publications

References 125 publications

Prevalence of <i>Toxoplasma gondii</i> antibodies in wild boar (Sus scrofa) from Strzałowo Forest Division, Warmia and Mazury Region, Poland

Prevalence of <i>Toxoplasma gondii</i> antibodies in wild boar (Sus scrofa) from Strzałowo Forest Division, Warmia and Mazury Region, Poland

Periodontitis and risk for preeclampsia — a systematic review

Hsv Infection is Associated with Gestational Hypertension: Results from the Us National Inpatient Sample

Contact Info

Product

Resources

About