“…fibroblasts, chondrocytes, lymphocytes, endothelial cells) is known to be trapped in insoluble multimeric fibrils, while that present in plasma (produced by hepatocytes) is released to the blood as a compact globular dimer [3,5]. The milk FN could originate from local synthesis by mammary epithelial cells, lymphocytes, and macrophages, and also part of it might originate from filtration of the blood [1]. FN mediates cellular interactions and plays important roles in cell adhesion, migration, proliferation, differentiation, tissue repair and extracellular matrix remodeling [5,6].…”