Human Papillomavirus in Thai Women and Men with Anogenital Warts

Nilyanimit, Pornjarim; Chansaenroj, Jira; Srisomboon, Jatupol; Rodrangnok, Wanida; Rajakom, Ngamta; Daengsaard, Ekkachai; Sookrak, Nutthavit; Poovorawan, Yong

doi:10.1159/000497351

Cited by 12 publications

(7 citation statements)

References 39 publications

(40 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The rate of HPV infection in the participants with EGL (67.79%) was similar to that reported in other studies (72.3% in Brazil, 61.3% in the USA, and 61.9% in Mexico - HIM Study), but lower than the results obtained in Thailand (88.3%), Turkey (75.8%), Colombia (88.9%), China (97.0%) and Ireland (78%) [ 13 , 14 , 33 – 36 ]. The discrepancy between these results could be due to differences in the sampling techniques or methods, misdiagnoses or true differences among the populations.…”

Section: Discussionsupporting

confidence: 88%

Sex differences in the prevalence and determinants of HPV-related external genital lesions in young adults: a national cross-sectional survey in Brazil

et al. 2020

View full text Add to dashboard Cite

Background External genital lesions (EGL) are the most common sexually transmitted infections (STIs). We aimed to evaluate the prevalence, determinants and sex differences in EGL among young adults from Brazil. Methods Overall, 7694 participants (aged 16 to 25 years) underwent an interview, genital examination and sampling for HPV genotyping. Results The prevalence of EGL was 4.08% (234) and is more frequent in men (5.72%) than women (2.31%) (p < 0.001). Genital lesions were significantly associated with male sex, infection by high-risk and multiple HPV types, having more than two sexual partners in the last year, smoking status and the presence of other STI. While alcohol use was associated with a higher prevalence of EGL in women, same-sex sexual relationship increase the prevalence in men. In the EGL group, 67.79% (p = 0.032) were positive for HPV infection and the types HPV6 and HPV11 were the most prevalent ones. Conclusion The prevalence of EGL in young adults was consistently high, and most cases were associated with genital HPV infection and STIs. Although men have a higher prevalence, both sexes share most genital lesion determinants. The promotion of sexual education and vaccination especially focus in young men, who are usually outside the targets of primary health care programmes, can prevent EGL in Brazilian young adults.

show abstract

Section: Discussionsupporting

confidence: 88%

Sex differences in the prevalence and determinants of HPV-related external genital lesions in young adults: a national cross-sectional survey in Brazil

et al. 2020

View full text Add to dashboard Cite

show abstract

“…is result is consistent with the previous studies in ailand, the United States, Brazil, Mexico, and China [17][18][19][20]. We also found that coinfections with multiple types of HPV were frequent, which is in agreement with prior studies [21].…”

Section: Discussionsupporting

confidence: 93%

Efficacy and Safety of Clinacanthus nutans Lindau Cream vs. Podophyllin for the Treatment of Adults with Condyloma Acuminata

Jiamton

Chanyachailert

Nanchaipruek

et al. 2022

Evidence-Based Complementary and Alternative Medicine

View full text Add to dashboard Cite

Human papillomavirus (HPV) infection causes condyloma acuminata (CA). Podophyllin is the standard treatment. Clinacanthus nutans Lindau (C. nutans), a medicinal plant, has potent anti-inflammatory and antiviral effects. C. nutans cream is widely used in Thailand to treat the herpes simplex virus. We proposed that C. nutans might also induce CA clearance. There are no studies of C. nutans treatment of CA. This randomized controlled trial at Siriraj Hospital, Thailand, was conducted between January 2018 and December 2019. CA samples were obtained from 10 men with at least two CAs 1 centimeter apart. Each wart was randomized to a 4-week treatment with either C. nutans or podophyllin. The participants were 24 to 72 years old. Most HPV types were low-risk HPVs (HPV 11, HPV 6). Median CA clearance with podophyllin was a 97% CA clearance with podophyllin and 82% with C. nutans. C. nutans may be an alternative treatment for CA.

show abstract

“…Consistent with previous studies, we used anal exfoliated cells to assess HPV infection in CA patients as in previous studies 31,32 . HPV infection in the anal region can be more comprehensively reflected by wiping CA lesions and anal canal.…”

Section: Discussionmentioning

confidence: 82%

“…Path analysis of the influencing factors for oncogenic HPV, HPV16, HPV52 infection among patients with anal CA (Table 5 and Consistent with previous studies, we used anal exfoliated cells to assess HPV infection in CA patients as in previous studies. 31,32 HPV infection in the anal region can be more comprehensively reflected by wiping CA lesions and anal canal. Multi-site sampling can promote more infections to be detected, which is beneficial to provide a basis for further exploring the risk factors of carcinogenic HPV infection.…”

Section: Sem Of Influencing Factors For Oncogenic Hpv Hpv16 Hpv52 Inf...mentioning

confidence: 99%

Prevalence and risk factors of anal human papillomavirus infection among men with anal condyloma acuminata by HIV status in ShenZhen, Southeast China: A retrospective cohort study

Liu,

Yang,

Huang

et al. 2023

Journal of Medical Virology

View full text Add to dashboard Cite

Patients with anal condyloma acuminatum (CA) are at risk of developing anal cancer which is associated with oncogenic human papillomavirus (HPV) infection. Investigation of anal HPV prevalence and risk factors can provide effective strategies for the prevention of anal cancer. A retrospective study was conducted among 549 patients with anal CA in the Third People's Hospital of Shenzhen between January 2019 and October 2021. HPV prevalence and HIV antibodies were detected by fluorescent PCR and ELISA, respectively. Logistic regression model and structural equation modeling (SEM) were conducted to analyzed the risk factors of oncogenic HPV infection. The overall prevalence of HPV was 96.72%. Both HPV6 (N = 285, 51.91%) and HPV11 (N = 300, 54.64%) were more than half infected and the most frequent Hr‐HPV genotype was HPV16 (N = 138, 25.14%). HIV‐positive (AOR: 5.02, 95% CI: 2.98−8.60, p < 0.0001) and history of syphilis (AOR: 4.24, 95% CI: 2.31−8.46, p < 0.0001) were independent risk factors statistically associated with oncogenic HPV infection. Ever had anal sex (AOR: 3.40, 95% CI: 1.28−11.81, p = 0.0267) and age 35 years and older (AOR: 2.79, 95% CI: 1.53−5.15, p = 0.0009) were associated with HPV16 and HPV52, respectively. SEM analyses showed that HIV‐positive (b = 1.549, p < 0.001) and history of syphilis (b = 1.450, p < 0.001) had significant positive effects on oncogenic HPV infection. Ever had anal sex (b = 1.243, p = 0.025) and Age (b = 0.043, p = 0.002) positively drived HPV16 and HPV52 infection, respectively. Anal CA patients who are HIV‐positive, have a history of syphilis, or at least 35 years old should be considered for Hr‐HPV, cytology and other anal cancer related tests to reduce the risk of cancer development.

show abstract

Human Papillomavirus in Thai Women and Men with Anogenital Warts

Cited by 12 publications

References 39 publications

Sex differences in the prevalence and determinants of HPV-related external genital lesions in young adults: a national cross-sectional survey in Brazil

Sex differences in the prevalence and determinants of HPV-related external genital lesions in young adults: a national cross-sectional survey in Brazil

Efficacy and Safety of Clinacanthus nutans Lindau Cream vs. Podophyllin for the Treatment of Adults with Condyloma Acuminata

Prevalence and risk factors of anal human papillomavirus infection among men with anal condyloma acuminata by HIV status in ShenZhen, Southeast China: A retrospective cohort study

Contact Info

Product

Resources

About