The hydrologic regime of a river is one of the factors determining its ecological status. This paper tries to indicate the present hydrologic stress occurring across European rivers on the basis of model integration. This results in a pan-European assessment at the resolution of the functional elementary catchment (FEC), based on simulated daily time-series of river flows from the model PCR-GLOBWB. To estimate proxies of the present hydrologic stress, two datasets of river flow were simulated under the same climate, one from a hypothetic least disturbed condition scenario and the second from the anthropogenic scenario with the actual water management occurring. Indicators describing the rivers' hydrologic regime were calculated with the indicators of hydrologic alteration (IHA) software package and the river total mean flow and the relative baseflow magnitude over the total flow were used to express the deviations between the two scenarios as proxy metrics of rivers' hydrologic alteration or hydrologic stress. The alteration results on Europe's FEC-level background showed that Southern Europe is more hydrologically stressed than the rest of Europe, with greater potential for hydrology to be clearly associated with river segments of unreached good ecological status and high basin management needs.Water 2019, 11, 703 2 of 17 shapes the patterns of erosion and sedimentation, and influences the type and dynamics of the river channels, banks and floodplains [1]. The hydrologic regime affects water chemistry through processes of retention, dilution or concentration. By this, it constitutes the habitat template for the riverine biota. Hydrology is thus an indispensable component of riverine ecology, and anthropogenic alteration of the hydrologic regime entails ecological detriment [2].Riverine hydrology is altered by humans in various ways [3,4]. At the local to regional scale, water abstraction, water diversion, water drainage and channelization modify the flow regime for the benefit of domestic, industrial or agricultural supply. In particular, dams represent one of the major anthropogenic disturbances of the rivers' hydrologic regimes [5]. At the river basin scale, the water retention capacities are reduced by converting natural vegetation into land used for agriculture or urbanization. At the continental scale, patterns of precipitation and evaporation shift due to a changing climate, with important changes in climate extremes over time. These alterations impact on the riverine ecosystems and lead to changes in natural flows, including water scarcity or overabundance with implications for ecological status and ecosystem services [6,7].However, full understanding of the effects of hydrologic alteration is still not available [8]. On the one hand, this relates to the intricate features of riverine hydrology covering the elements of timing, magnitude, duration and frequency, all of which are integral components of the ecosystem [9]. On the other hand, this relates to the lack of comprehensive datasets, e.g., from strea...