Human Toxicology of Pesticides

Kaloyanova, Fina P.; Batawi, Mostafa A. El

doi:10.1201/9780429266775

Cited by 16 publications

(7 citation statements)

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“…In addition, the absorption intensity increased at 280 nm, and a bathochromic effect was observed due to the interaction of Cartap and globin through hydrophobic interaction and the change in shape, which was confirmed by molecular docking analysis. In addition, a decrease in the Soret band and Q peak was observed, 1 Tetraethyl pyrophosphate 2…”

Section: Interaction Of Cartap With Hemoglobinmentioning

confidence: 99%

“…TEPP 1 can dissolve REC and enter red blood cells; also, it can interact with the heme prosthetic group (internal) and induce heme degradation when interacting with Hb. 2 LIGPLOT analysis of this interaction (Figure 2a) shows that TEPP interacts hydrophobically with aromatic moieties. Docking studies also confirmed the penetration of TEPP into the hydrophobic pocket (Figure 2b).…”

Section: Interaction Of Tetraethyl Pyrophosphate With Hemoglobinmentioning

confidence: 99%

“…Almost 2 million tons of pesticides are used worldwide each year, overgrowing. Pesticides directly or indirectly contaminate air, water, soil, and entire ecosystems, posing a severe threat to the health of living things [2,3].…”

Section: Introductionmentioning

confidence: 99%

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Biological and Molecular Effects of Pesticides on Human Health

Doroudian¹,

Emadi²,

Hosseinzadeh³

et al. 2022

Pesticides - Updates on Toxicity, Efficacy and Risk Assessment

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Pesticides are widely used in agriculture and are practical and economical to improve the quality of food safety for the permanent population around the world. Even though insecticides are beneficial to cropping views, their extensive use may result in severe consequences due to their biocompatible and permanent nature. Various pesticides can cause serious health risks of direct or indirectly contaminated air, water, soil, and the general ecosystem. The effect of pesticides on blood in the mammalian cell is significant because blood can act as a target and carrier for pesticides. However, the mechanism by which they bind to biopolymers, particularly blood proteins, is not clearly understood yet. This chapter investigates the molecular effects of pesticides on biomacromolecules, especially hemoglobin.

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Section: Interaction Of Cartap With Hemoglobinmentioning

confidence: 99%

Section: Interaction Of Tetraethyl Pyrophosphate With Hemoglobinmentioning

confidence: 99%

See 1 more Smart Citation

Biological and Molecular Effects of Pesticides on Human Health

Doroudian¹,

Emadi²,

Hosseinzadeh³

et al. 2022

Pesticides - Updates on Toxicity, Efficacy and Risk Assessment

View full text Add to dashboard Cite

show abstract

“…-ketoglutaroxidase, pyruvate dehydrogenase, succinic dehydrogenase). Typical clinical presentations for acute over-exposure are headache, weakness, excitability, nausea, vomiting, diarrhoea, abdominal discomfort, dizziness, and coma (Kaloyanova and Batawi, 1991). Carbon disulphide (and its metabolites) are the only compounds common to the metabolism of dithiocarbamate fungicides.…”

Section: Dithiocarbamate Fungicidesmentioning

confidence: 99%

“…The high toxicity of organotin compounds is reflected in their low occupational exposure limits: TWA 8 ¼ 0.1 mg=m 3 , STEL 0.2 mg=m 3 (ACGIH, 2003). Detailed reviews can be found in Kaloyanova and Batawi (1991) and WHO (1980WHO ( , 1990a.…”

Section: Organometallic Fungicidesmentioning

confidence: 99%