Conservation efforts under the nature-based solutions (NbS) framework aim at better management of ecosystems and improvement of human well-being. Policies targeting forest-based livelihoods align well with the NbS principles, but their social-ecological outcomes are often confounded by complex human-environment interactions. In this study, we identify one major feedback effect of the ecosystem dynamic on people’s livelihoods based on datasets collected from two study areas in China and Nepal. Our methodology integrates satellite remote sensing, household surveys, and statistical models to investigate households’ cropland abandonment decisions under the influence of crop-raiding by wildlife. Results show that cropland parcels that have experienced crop-raiding are more likely to be abandoned in the following years. The more damage the crops have suffered on a given parcel, the more likely it is that the parcel will be abandoned. Parcels in proximity to natural forests, farther away from the house location, and with poorer access to paved roads bear a higher risk of being abandoned. These effects are robust and consistent after controlling for multiple parcel features and household characteristics at different levels and using the dataset from each study area separately. We conclude that policymakers need to consider this undesirable feedback of the ecological system to the livelihoods of local people to better achieve co-benefits for ecosystems and human society.