Humic acid mitigated toxicity of graphene-family materials to algae through reducing oxidative stress and heteroaggregation

Zhao, Jian; Li, Yue; Cao, Xuesong; Guo, Chuntong; Xu, Lei; Wang, Zhengyu; Feng, Jiao; Yi, Huimin; Xing, Baoshan

doi:10.1039/c9en00067d

Cited by 31 publications

(20 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…graphene (oxide) and carbon nanotubes (CNT)) are not entirely clear with conflicting evidence presented in the literature. [6][7][8][9][10][11] The perceived toxicity of graphene (oxide) and CNT have been attributed to their accumulation in main organs with low to no specific clearance pathway, similar to other types of two dimensional layered materials. [12][13][14][15] To circumvent the potential toxicity of graphene (oxide), ultra-small graphene derivatives have been developed, known as graphene quantum dots (GQDs).…”

Section: Introductionmentioning

confidence: 99%

Influence of surface charge of graphene quantum dots on their uptake and clearance in melanoma cells

2021

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Influence of surface charge of graphene quantum dots on their uptake and clearance in melanoma cells

2021

View full text Add to dashboard Cite

show abstract

“…These results are contradictory with the vast majority of single-species-based studies which indicated that exposure to engineered nanoparticles led to algal growth inhibition associated to oxidative stress induced by cellular damages ( Chen et al, 2019 ; Saxena et al, 2020 ). For example, this was observed for green pelagic algae such as Raphidocelis subcapitata , Chlorella pyrenoidosa , or Scenedesmus obliquus after exposure to GO or rGO ( Du et al, 2016 ; Zhao et al, 2017 , 2019 ; Malina et al, 2019 ). It was also indicated that the exposure of the freshwater diatom N. palea to few layer graphene (FLG) increased the production of EPS substances which mitigated its toxicity ( Garacci et al, 2017 , 2019 ).…”

Section: Discussionmentioning

confidence: 92%

Graphene-Based Nanomaterials Modulate Internal Biofilm Interactions and Microbial Diversity

et al. 2021

View full text Add to dashboard Cite

Graphene-based nanomaterials (GBMs), such as graphene oxide (GO) and reduced graphene oxide (rGO), possess unique properties triggering high expectations for the development of new technological applications and are forecasted to be produced at industrial-scale. This raises the question of potential adverse outcomes on living organisms and especially toward microorganisms constituting the basis of the trophic chain in ecosystems. However, investigations on GBMs toxicity were performed on various microorganisms using single species that are helpful to determine toxicity mechanisms but fail to predict the consequences of the observed effects at a larger organization scale. Thus, this study focuses on the ecotoxicological assessment of GO and rGO toward a biofilm composed of the diatom Nitzschia palea associated to a bacterial consortium. After 48 and 144 h of exposure to these GBMs at 0, 0.1, 1, and 10 mg.L−1, their effects on the diatom physiology, the structure, and the metabolism of bacterial communities were measured through the use of flow cytometry, 16S amplicon sequencing, and Biolog ecoplates, respectively. The exposure to both of these GBMs stimulated the diatom growth. Besides, GO exerted strong bacterial growth inhibition as from 1 mg.L−1, influenced the taxonomic composition of diatom-associated bacterial consortium, and increased transiently the bacterial activity related to carbon cycling, with weak toxicity toward the diatom. On the contrary, rGO was shown to exert a weaker toxicity toward the bacterial consortium, whereas it influenced more strongly the diatom physiology. When compared to the results from the literature using single species tests, our study suggests that diatoms benefited from diatom-bacteria interactions and that the biofilm was able to maintain or recover its carbon-related metabolic activities when exposed to GBMs.

show abstract

“…A high concentration of tetracycline induced high oxidative stress. Humic acid addition reduced oxidative damage and associated oxidative stress biomarkers, most probably due to (bio)chemical priming of secondary metabolism and the microalgae detoxification and defense systems [ 91 ].…”

Section: Protective Effects Of Humic Substances On Microalgaementioning

confidence: 99%

Humic Substances as Microalgal Biostimulants—Implications for Microalgal Biotechnology

Popa

Lupu

Constantinescu-Aruxandei

et al. 2022

Marine Drugs

View full text Add to dashboard Cite

Humic substances (HS) act as biostimulants for terrestrial photosynthetic organisms. Their effects on plants are related to specific HS features: pH and redox buffering activities, (pseudo)emulsifying and surfactant characteristics, capacity to bind metallic ions and to encapsulate labile hydrophobic molecules, ability to adsorb to the wall structures of cells. The specific properties of HS result from the complexity of their supramolecular structure. This structure is more dynamic in aqueous solutions/suspensions than in soil, which enhances the specific characteristics of HS. Therefore, HS effects on microalgae are more pronounced than on terrestrial plants. The reported HS effects on microalgae include increased ionic nutrient availability, improved protection against abiotic stress, including against various chemical pollutants and ionic species of potentially toxic elements, higher accumulation of value-added ingredients, and enhanced bio-flocculation. These HS effects are similar to those on terrestrial plants and could be considered microalgal biostimulant effects. Such biostimulant effects are underutilized in current microalgal biotechnology. This review presents knowledge related to interactions between microalgae and humic substances and analyzes the potential of HS to enhance the productivity and profitability of microalgal biotechnology.

show abstract

Humic acid mitigated toxicity of graphene-family materials to algae through reducing oxidative stress and heteroaggregation

Abstract: HA alleviated GFM-induced membrane damage by reducing oxidative stress and heteroaggregation.

Cited by 31 publications

References 38 publications

Influence of surface charge of graphene quantum dots on their uptake and clearance in melanoma cells

Influence of surface charge of graphene quantum dots on their uptake and clearance in melanoma cells

Graphene-Based Nanomaterials Modulate Internal Biofilm Interactions and Microbial Diversity

Humic Substances as Microalgal Biostimulants—Implications for Microalgal Biotechnology

Contact Info

Product

Resources

About