Hurthle Cell Carcinoma Metastatic to Uterus

Abstract

Background. The authors present a case of Hiirthle cell carcinoma metastatic to the uvea in a patient with known Hiirthle cell tumor of the thyroid. The fluorescein angiogram suggested a neoplastic lesion, and the collar-button configuration resembled a malignant melanoma. However, standardized echography revealed high internal reflectivity and an irregular acoustic structure suggestive of a metastatic carcinoma. Methods. The clinical history and examination were consistent with the diagnosis of metastatic Hiirthle cell carcinoma of the eye. Results of a fine-needle aspiration biopsy and histopathology of the intraocular lesion confirmed the diagnosis. Results. Because this was the patient's better-seeing eye, the tumor was treated with an lZ5I radioactive epi-scleral plaque. Over the subsequent 27 months, the lesion demonstrated a gradual regression. Conclusions. We have not found any previously reported cases of Hiirthle cell carcinoma of the thyroid met-astatic to the eye. The diagnosis may be confirmed safely by intraocular aspiration biopsy. The lesion is responsive to radioactive plaque application. The origin, pathology , and management of this unusual tumor are reviewed. Cancer 1994; 73:163-7.

Hürthle Cell Thyroid Carcinoma Metastatic to the Sigmoid Colon

“…In a recent retrospective study, they were observed in respectively 50% and 64% of patients with metastatic FTC and respectively 80% and 39% of patients with metastatic papillary thyroid carcinoma (5). Other sites are infrequent but metastases to kidney, brain, skin, liver, salivary glands, ovary, uterus, or adrenal gland have been reported, mainly as case reports (9)(10)(11)(12)(13). In this case history, the patient operated on at 56 years, for a large FTC with extracapsular involvement was at high risk of recurrence.…”

Thyroid Cancer Brain Metastases and Thyroglobulin

“…Patients with recurrent disease outside the neck structures usually show lung micrometastases or bone infiltrations [5]. Brain metastases (BMs) from TC, however, are quite rare, involving only 0.5-2.3% of all DTC cases [6][7][8][9][10][11][12]. Prognosis is usually poor due to its high morbidity and mortality rates.…”