Hyaline cartilage: truncation artifact as a cause of trilaminar appearance with fat-suppressed three-dimensional spoiled gradient-recalled sequences.

Erickson, S J; Waldschmidt, James G.; Czervionke, Leo F.; Prost, Robert

doi:10.1148/radiology.201.1.8816555

Cited by 84 publications

(36 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A laminated appearance of the articular cartilage is commonly seen on MR imaging. This laminar appearance within the articular cartilage on FS 3D GE images is predominantly attributable to truncation artefact due to under-sampling of the high spatial frequencies rather than to histological zonal anatomy (Figure 4) (Erickson et al 1996, Frank et al 1997, Waldschmidt et al 1997. The current author has reported this laminated appearance in growth plate cartilage in rats ( Figure 5, Wang et al 2006b).…”

Section: Imaging Artefactsmentioning

confidence: 70%

In vivo magnetic resonance imaging of animal models of knee osteoarthritis

Wáng

2008

Lab Anim

View full text Add to dashboard Cite

SummaryRecent technical developments in high-field magnetic resonance (MR) scanners, improvement in radio frequency coil design and gradient performance along with the development of efficient pulse sequences and new methods of enhancing contrast have made high-quality imaging of animal arthritis models feasible. MR can provide high-resolution structural information about the osteoarthritic changes in animal models, and also information about the biophysical properties of cartilage. This paper reviews the MR techniques available for animal knee imaging, and the various MR-derived readouts of knee osteoarthritis in animal models. Pitfalls in interpreting animal joint anatomy and joint composition are highlighted.

show abstract

Section: Imaging Artefactsmentioning

confidence: 70%

In vivo magnetic resonance imaging of animal models of knee osteoarthritis

Wáng

2008

Lab Anim

View full text Add to dashboard Cite

show abstract

“…In other studies, high-resolution MR images of articular cartilage revealed a multilaminar appearance reflecting distinct anatomical zones, but it was also reported that a false laminar appearance can be created by MR imaging truncation artifacts from opposing cartilage edges (8,9). Different T2 relaxation times have also been measured as a function of cartilage depth.…”

Section: Introductionmentioning

confidence: 98%

MRI heterogeneity of articular cartilage in strong magnetic fields: Dependence on proteoglycan content

Othman

Williams

Sumner

et al. 2004

Concepts Magn Reson

View full text Add to dashboard Cite

Articular cartilage is a thin heterogeneous tissue (typical thickness of less than 2 mm) composed of collagen, proteoglycan, and water that coats skeletal joint surfaces. Its physical and chemical integrity are essential for maintaining normal joint articulation. MR imaging techniques are being developed to visualize articular cartilage for the purpose of assessing changes in its structure that occur with age and the onset of joint disease. Emerging high-field MR systems (greater than 4 T) have a higher signal-to-noise ratio, which can be used to improve the spatial resolution for imaging articular cartilage beyond that available in most clinical systems. In this study, we examined the effect of changing the proteoglycan content of articular cartilage on high-resolution (40 ϫ 40 ϫ 100 m) T1-and T2-weighted images acquired at 11.74 T (500 MHz for protons). Susceptibility artifacts were observed near the cartilage-bone interface that were verified by separating the cartilage from the bone. MR image heterogeneity of articular cartilage was observed as a function of depth and in the transverse directions of the sample. Enzymatic depletion of cartilage proteoglycan demonstrated that the MR image heterogeneity is due in part to variation of the proteoglycan content in different regions of the cartilage. The apparent diffusion coefficient (ADC) was measured as a function of depth in the cartilage. The ADC varied from the subchondral bone to the articular surface for both normal and digested cartilage. In addition, the ADC increased by 20% after 6 hours of enzymatic digestion of proteoglycan. These results suggest a role for high-field MRI of articular cartilage in the management and staging of osteoarthritis and other joint diseases.

show abstract

“…In addition, these sequences seemed to provide biochemical information of AC. This was based on the observation that the laminar appearance of AC correlated with layers that differed in proteoglycan (PG) contents [16], although other investigators have questioned the laminar appearance of AC on 3-D SPGR and rather attributed the changes in signal intensity to technical artifacts [3,4]. These previous observations, however, cannot be directly applied to companion animals since most of the studies have been performed on the knee AC, which is easy to obtain high quality images on MRI because of its location and thickness.…”

mentioning

confidence: 99%

High Field (4.7T) Magnetic Resonance Imaging of Feline Hip Joints

Kamishina

Miyabayashi

Clemmons

et al. 2006

The Journal of Veterinary Medical Science

View full text Add to dashboard Cite

ABSTRACT. Magnetic resonance imaging (MRI) is a non-invasive technique widely used to investigate degenerative joint disease (DJD). In this study, we obtained magnetic resonance images of feline hip joints, using a high magnetic field MRI unit (4.7 tesla) with proton density (PD)-weighted and T2-weighted fast spin-echo (FSE). PD-weighted FSE provided detailed anatomical images of feline hip joints with superb depiction of subchondral bones of the femoral head and acetabulum. Articular cartilage (AC) was also visualized with PDweighted and T2-weighted FSE; however, mild AC lesions noted on gross examination were not detectable with these sequences. KEY WORDS: degenerative joint disease, feline, magnetic resonance imaging.

show abstract

Hyaline cartilage: truncation artifact as a cause of trilaminar appearance with fat-suppressed three-dimensional spoiled gradient-recalled sequences.

Abstract: The trilaminar appearance depicted within hyaline cartilage on MR images obtained with this sequence is predominantly attributable to truncation artifact rather than to histologic zonal anatomy.

Cited by 84 publications

References 0 publications

In vivo magnetic resonance imaging of animal models of knee osteoarthritis

In vivo magnetic resonance imaging of animal models of knee osteoarthritis

MRI heterogeneity of articular cartilage in strong magnetic fields: Dependence on proteoglycan content

High Field (4.7T) Magnetic Resonance Imaging of Feline Hip Joints

Contact Info

Product

Resources

About