Hyaluronic acid/corn silk extract based injectable nanocomposite: A biomimetic antibacterial scaffold for bone tissue regeneration

Makvandi, Pooyan; Ali, Ghareib W.; Sala, Francesca Della; Abdel-Fattah, Wafa I.; Borzacchiello, Assunta

doi:10.1016/j.msec.2019.110195

Cited by 165 publications

(104 citation statements)

References 41 publications

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“…Silver‐based nanocompounds are by far the most frequently used commercial nanoparticle [ 146 ] because of their potent antibacterial, antifungal and antiviral activities. [ 147–149 ] Silver nanostructures display potent antimicrobial activities that are comparable with Ag ions. [ 150 ] Silver and silver oxide (Ag 2 O) nanoparticles have diverse antibacterial applications in dentistry, [ 105,111,151 ] as scaffolds for tissue engineering [ 152,153 ] and as wound healing materials.…”

Section: Metal‐based Nanocompoundsmentioning

confidence: 99%

Metal‐Based Nanomaterials in Biomedical Applications: Antimicrobial Activity and Cytotoxicity Aspects

Makvandi

Wang

Zare

et al. 2020

Adv Funct Materials

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520

368

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Microbial colonization on material surfaces is ubiquitous. Biofilms derived from surface-colonized microbes pose serious problems to the society from both an economical perspective and a health concern. Incorporation of antimicrobial nanocompounds within or on the surface of materials, or by coatings, to prevent microbial adhesion or kill the microorganisms after their attachment to biofilms, represents an important strategy in an increasingly challenging field. Over the last decade, many studies have been devoted to preparing meta-based nanomaterials that possess antibacterial, antiviral, and antifungal activities to combat pathogen-related diseases. Herein, an overview on the state-of-the-art antimicrobial nanosized metal-based compounds is provided, including metal and metal oxide nanoparticles as well as transition metal nanosheets. The antimicrobial mechanism of these nanostructures and their biomedical applications such as catheters, implants, medical delivery systems, tissue engineering, and dentistry are discussed. Their properties as well as potential caveats such as cytotoxicity, diminishing efficacy, and induction of antimicrobial resistance of materials incorporating these nanostructures are reviewed to provide a backdrop for future research.

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Section: Metal‐based Nanocompoundsmentioning

confidence: 99%

Metal‐Based Nanomaterials in Biomedical Applications: Antimicrobial Activity and Cytotoxicity Aspects

Makvandi

Wang

Zare

et al. 2020

Adv Funct Materials

Self Cite

520

368

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“…Such polymer nanocomposites possess a wide range of applications including medical devices, aerospace engineering, and automotive components [1]. For instance, nanocomposites reinforced with some polymeric and inorganic nanofillers such as chitosan nanoparticles and silver nanoparticles have been proven to be effective for antimicrobial treatment in dentistry [8] or for bone tissue regeneration [9]. Other studies [10,11] demonstrated that polymer nanocomposites, as exemplified by polypropylene (PP)/clay nanocomposites, have real automotive industrial potential to result in significant property improvement with only minor increasing cost if a deeper understanding of their structure-property relationship can be achieved.…”

Section: Introductionmentioning

confidence: 99%

The Role of Nanoparticle Shapes and Structures in Material Characterisation of Polyvinyl Alcohol (PVA) Bionanocomposite Films

Mousa

Dong

2020

Polymers

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Three different types of nanoparticles, 1D Cloisite 30B clay nanoplatelets, 2D halloysite nanotubes (HNTs), and 3D nanobamboo charcoals (NBCs) were employed to investigate the impact of nanoparticle shapes and structures on the material performance of polyvinyl alcohol (PVA) bionanocomposite films in terms of their mechanical and thermal properties, morphological structures, and nanomechanical behaviour. The overall results revealed the superior reinforcement efficiency of NBCs to Cloisite 30B clays and HNTs, owing to their typical porous structures to actively interact with PVA matrices in the combined formation of strong mechanical and hydrogen bondings. Three-dimensional NBCs also achieved better nanoparticle dispersibility when compared with 1D Cloisite 30B clays and 2D HNTs along with higher thermal stability, which was attributed to their larger interfacial regions when characterised for the nanomechanical behaviour of corresponding bionanocomposite films. Our study offers an insightful guidance to the appropriate selection of nanoparticles as effective reinforcements and the further sophisticated design of bionanocomposite materials.

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“…A potential scaffold frontier for bone tissue engineering protocols seems to be the mesenchymal stem cells seeded in nanocomposite materials with antibacterial properties, but further studies in this direction are necessary prior to be consider it as a safe and useful tool for human implantation purposes [40].…”

Section: Discussionmentioning

confidence: 99%

Design Techniques to Optimize the Scaffold Performance: Freeze-dried Bone Custom-made Allografts for Maxillary Alveolar Horizontal Ridge Augmentation

Grassi

Vivarelli

et al. 2020

Materials

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The purpose of the current investigation was to evaluate the clinical success of horizontal ridge augmentation in severely atrophic maxilla (Cawood and Howell class IV) using freeze-dried custom made bone harvested from the tibial hemiplateau of cadaver donors, and to analyze the marginal bone level gain prior to dental implant placement at nine months subsequent to bone grafting and before prosthetic rehabilitation. A 52-year-old woman received custom made bone grafts. The patient underwent CT scans two weeks prior and nine months after surgery for graft volume and density analysis. The clinical and radiographic bone observations showed a very low rate of resorption after bone graft and implant placement. The custom-made allograft material was a highly effective modality for restoring the alveolar horizontal ridge, resulting in a reduction of the need to obtain autogenous bone from a secondary site with predictable procedure. Further studies are needed to investigate its behavior at longer time periods.

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Hyaluronic acid/corn silk extract based injectable nanocomposite: A biomimetic antibacterial scaffold for bone tissue regeneration

Cited by 165 publications

References 41 publications

Metal‐Based Nanomaterials in Biomedical Applications: Antimicrobial Activity and Cytotoxicity Aspects

Metal‐Based Nanomaterials in Biomedical Applications: Antimicrobial Activity and Cytotoxicity Aspects

The Role of Nanoparticle Shapes and Structures in Material Characterisation of Polyvinyl Alcohol (PVA) Bionanocomposite Films

Design Techniques to Optimize the Scaffold Performance: Freeze-dried Bone Custom-made Allografts for Maxillary Alveolar Horizontal Ridge Augmentation

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