Hyaluronic Acid Nanofibers Electrospun From Water-Organic Solutions

Abstract

This paper briefly concerns the principle of obtaining polymer fibers and particles of nano-and microscale level from aqueous-organic solutions of hyaluronic acid via electrospinning. The formulation and method of obtaining spinning solutions are analyzed. The study deals with the primary results of utilizing of hyaluronic acid spinning solutions based on deionized water/dimethyl sulfoxide (DMSO) solvent mixtures without using additional modifying polymers. The influence of solvent ratios and polymer concentration on the diameter of obtained hyaluronic acid nanofibers was investigated. The prospects of using the obtained fiber materials in the field of medical and bioengineering applications are shown.