Hybrid Heterostructures for SPR Biosensor

Abstract

Surface plasmon resonance (SPR) based biosensors have been enormously studied in the last decade for their better sensitivity. In recent years hybrid heterostructures are getting popularity to implement these SPR biosensors for their superior sensing capability. This chapter demonstrates the details of SPR technology with two recently studied prism-based hybrid heterostructures. These heterostructures are made up of conventional SPR biosensors with two additional layers of recently invented transition metal dichalcogenides, platinum di-selenide (PtSe2), and highly sensitive 2D material, tungsten di-sulfide (WS2). Angular interrogation method is discussed to investigate the sensing capabilities of the sensors which prove the superiority of the Ag-PtSe2-WS2 structure. The sensing capability of this structure has been found at least 1.67 times higher than that of the conventional non-hybrid structures, respectively, with comparable FOM and QF. A comparison table has been provided at the end of this chapter which also shows the impressive performance of the hybrid heterostructures for SPR biosensors. Proper demonstration with a suitable example of this chapter will emphasize the potential use of hybrid heterostructure based SPR biosensors in prospective medical diagnostics and biomedical detection applications.

Performance Enhancement of Surface Plasmon Resonance Sensor Based on 2D Nanomaterial

“…Another way to measure the efficiency of the proposed sensor is the figure of merit (FOM), it is simple to calculate it from the previous relations; it is the ratio of the sensitivity to the FWHM [36]:…”

Recent Advances in Biosensors Based on Conducting Polymers for Biomedical Applications

“…[76,79,81,82] The applications of SPR biosensors cover a very wide area such as agriculture, food, monitoring product quality in agriculture, biology, medicine, diagnosis, imaging, cancer, enzyme detection and analysis of various molecules. [79,83,84]…”

“…Especially metals such as gold, copper, silver are the best plasmonic materials. [79,80] Surface plasmon resonance (SPR) biosensors are widely used due to their advantages such as affordability, high sensitivity, real-time sensing capabilities, sufficient sample size for measurement, anti interference capability, versatile target molecule selection and reusability. [76,79,81,82] The applications of SPR biosensors cover a very wide area such as agriculture, food, monitoring product quality in agriculture, biology, medicine, diagnosis, imaging, cancer, enzyme detection and analysis of various molecules.…”