2005
DOI: 10.1016/j.anndiagpath.2004.12.001
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Hybrid peripheral nerve sheath tumors: schwannoma-perineurioma and neurofibroma-perineurioma. A report of three cases in extradigital locations

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Cited by 86 publications
(64 citation statements)
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“…Although perineurioma has been first described in 1978 [19], it still represents a poorly recognised neoplasm in the spectrum of peripheral nerve sheath tumours [25], and, especially, examples of unusual histological variants cause considerable diagnostic problems and may be mistaken for different or more aggressive soft tissue tumours. Interestingly, rare examples of benign peripheral nerve sheath tumours showing a combination of perineurioma and schwannoma as well as of perineurioma and neurofibroma have been reported most recently [18,23]. In this review one case each of reticular and plexiform perineurioma is reported, and a review of perineurial neoplasms of skin and soft tissues is given.…”
Section: Introductionmentioning
confidence: 93%
“…Although perineurioma has been first described in 1978 [19], it still represents a poorly recognised neoplasm in the spectrum of peripheral nerve sheath tumours [25], and, especially, examples of unusual histological variants cause considerable diagnostic problems and may be mistaken for different or more aggressive soft tissue tumours. Interestingly, rare examples of benign peripheral nerve sheath tumours showing a combination of perineurioma and schwannoma as well as of perineurioma and neurofibroma have been reported most recently [18,23]. In this review one case each of reticular and plexiform perineurioma is reported, and a review of perineurial neoplasms of skin and soft tissues is given.…”
Section: Introductionmentioning
confidence: 93%
“…p.E547K S Hybrid neuri¢broma/ perineurioma (S) Kazakov et al [2005] Numbering according to cDNA sequence in Rouleau et al [1993] (GenBank Accession Number Z22664.1); nucleotide 11 is the A of the ATG initiation codon (which is codon 11). Changes at the protein level are theoretically deduced.…”
Section: Genotype^phenotype Relationships In Somatic Alterationsmentioning
confidence: 99%
“…Several histologic subtypes of soft tissue perineurioma have been described, the most important being the sclerosing [10] and reticular (retiform) variants [11]. Perineurioma may also present as a component of hybrid peripheral nerve sheath tumors [12]. In this report, we describe a parotid gland tumor with features of soft tissue perineurioma.…”
Section: Introductionmentioning
confidence: 88%