Hydatidosis in the province of La Pampa, Argentina, 1998.

Lamberti, Roberto; Calvo, Claudio; Pombar, Arian; Gino, Lilia Mabel; Álvarez, Eduardo; Aguado, Carlos; Larrieu, Edmundo

doi:10.4067/s0365-94021999000300013

Cited by 2 publications

(3 citation statements)

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“…EgAFFPf showed a higher specificity in tests with these potentially cross‐reactive sera, but it was associated with a significantly lower sensitivity. Cross‐reaction with T. solium is a major problem in CHD immunodiagnosis [9,37,38] and this disease is also prevalent in E. granulosus endemic areas, such as the Andean region and the South Cone of South America [39–45]. In the same regions, toxocariasis ( Toxocara spp.)…”

Section: Discussionmentioning

confidence: 99%

A set of recombinant antigens from Echinococcus granulosus with potential for use in the immunodiagnosis of human cystic hydatid disease

Virginio

Hernández

Rott

et al. 2003

Clinical and Experimental Immunology

101

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SUMMARYSeveral recombinant clones expressing antigens from Echinococcus granulosus were isolated previously from a parasite cDNA library using cystic hydatid disease (CHD) patients' sera or rabbit hyperimmune antiserum against a lipoproteic fraction from bovine cyst fluid. Six of these antigens were expressed in Escherichia coli and the purified recombinant proteins were tested in enzyme-linked immunosorbent assay (ELISA) for specific IgG with a panel of sera from patients with surgically confirmed ( n = 58) or immunologically diagnosed ( n = 71) CHD. Sera from clinically normal individuals ( n = 203) and sera from individuals with other helminthic infections ( n = 65) were assayed for the assessment of specificity. A cut-off value was determined by receiver-operating-characteristic plots for each antigen. A recombinant antigen B subunit (AgB8/2) presented the highest sensitivity (93·1%), considering the group of sera from patients with CHD surgically confirmed, and specificity (99·5%) and is proposed as the basis for an immunodiagnostic test. The other recombinant antigens tested presented sensitivities between 58·6% and 89·7%, and three of them were considered of complementary value. In subclass-specific ELISA, different IgG isotypes showed dominance in the response for each of the recombinant antigens. There was a clear predominance of IgG4 response for all antigens tested, indicating that this would be the subclass of choice to be assessed for these recombinant proteins.

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Section: Discussionmentioning

confidence: 99%

A set of recombinant antigens from Echinococcus granulosus with potential for use in the immunodiagnosis of human cystic hydatid disease

Virginio

Hernández

Rott

et al. 2003

Clinical and Experimental Immunology

101

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“…In the Pampa, flooding can be severe and Argentina hemorrhagic fever (AHF) is endemic (Polop et al 2008) within a humid environment. Cases of hantivirus (Porcasi et al 2005) and hydatidosis (Lamberti et al 1999) have also been recorded there.…”

Section: Resultsmentioning

confidence: 96%

“…It is interesting to note that Argentine hemorrhagic fever (AHF), as identified by Polop et al (2008), prevails where the NDVI modes 10 and 5 are found. Mode 10 is also in a zone where hantivirus dominates and can include preferred areas for rodents' habitats and reservoirs of zoonoses (Sergio Sosa-Estani et al 2001, Porcasi et al 2005 (Lamberti et al 1999), a region covered by mode 10. All of the above remarks warrant further statistical and quantitative investigations on the role climateenvironment variability can play in terms of spatio-temporal appearance and diffusion of diseases.…”

Section: Discussionmentioning

confidence: 99%

Spatio-temporal variability of NDVI–precipitation over southernmost South America: possible linkages between climate signals and epidemics

Tourre

Jarlan

Lacaux

et al. 2008

Environ. Res. Lett.

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Climate-environment variability affects the rates of incidence of vector-borne and zoonotic diseases and is possibly associated with epidemics outbreaks. Over southernmost South America the joint spatio-temporal evolution of climate-environment is analyzed for the 1982-2004 period. Detailed mapping of normalized difference vegetation index (NDVI) and rainfall variability are then compared to zones with preliminary epidemiological reports. A significant quasi-biennial signal (2.2-to 2.4-year periods, or QB) for joint NDVI-rainfall variability is revealed. From rotated EOFs, dominant NDVI patterns are partitioned according to their lead frequencies: (1) the 'QB group' (2.1-to 3-year periods) includes six modes over southern Brazil, Uruguay, northern-central Argentina (two modes), the southern Paraguay-northern Argentina border, and the Santa Cruz Province; (2) the QB1 (2.4-to 3-year periods) + quasi-quadrennial (QQ) mode over the Misiones Province; and (3) the QB2 (2.1-to 2.5-year periods) + QQ + inter-annual (IA) (3-to 7-year periods) two modes over south-eastern Argentina. Modes within the 'QB group' are positively correlated with global climate signals and SST. The Uruguayan mode is correlated with global ENSO (8-month lag) whilst the southern Entre-Rios/northern Buenos Aires provinces are correlated with central equatorial Pacific SSTs (3-month lag). The Santa Cruz (Patagonia) Province is most correlated with the Pacific South America (PSA) index and SST patterns (3-month lag) along the Antarctica circumpolar current. The spatial distribution of lead NDVI modes includes the Formosa, Misiones, Chaco and Buenos Aires provinces among others, known for being prone to vector-borne epidemics such as dengue fever, malaria, leishmaniasis (American cutaneous leishmaniasis or ACL), hantivirus, chagas and Argentine hemorrhagic fever (AHF). Some provinces also correspond to regions where lead NDVI PCs' modes are associated with high-frequency climate signals such as the quasi-biennial oscillation in northwest Argentina. The joint preliminary results (climate-environment-public health reports) presented here for the first time are meant: (1) to contribute to a better understanding of climate-environment-epidemics process-based and modeling studies and (2) to facilitate, in the long run, the implementation of local and regional health early warning systems (HEWS) over southernmost South America. The latter is becoming crucial with ever-increasing migration, urban sprawl (re-emergence of dengue fever epidemics since the late 1990s), all embedded in a climate change context.

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Hydatidosis in the province of La Pampa, Argentina, 1998.

Cited by 2 publications

References 0 publications

A set of recombinant antigens from Echinococcus granulosus with potential for use in the immunodiagnosis of human cystic hydatid disease

A set of recombinant antigens from Echinococcus granulosus with potential for use in the immunodiagnosis of human cystic hydatid disease

Spatio-temporal variability of NDVI–precipitation over southernmost South America: possible linkages between climate signals and epidemics

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