Hydrazone as a new fluorophore in the peroxyoxalate chemiluminescence reaction

Prevent or Cure—The Unprecedented Need for Self‐Reporting Materials

“…[124,[126][127][128][129][130] Therefore,CLreactions find widespread applications in biomedical or analytical fields with ongoing research for persistent improvement. However,the challenge to gain higher CL quantum yields,tune the emission range,or simplify the CL system is to modify the reaction environment or the luminophore itself in such away that the CL properties are not diminished accidentally.Nevertheless,recent research into common luminophores,s uch as dioxetanes, [131,132] peroxyoxalates (POs), [122,[133][134][135][136][137] acridinium esters, [138][139][140][141] luminol, [129,142] and their respective derivatives,led to the development of aplethora of advanced, promising self-reporting CL systems.T he CL of acridinium esters,f or example,c an be triggered by antioxidants,e nzymes or peroxides and thus finds application in (biomedical) analytics as self-reporting sensor for these substances. [138][139][140][141] In the presence of atrigger, the acridinium esters are oxidized to dioxetanones,w hich decompose with the release of CO 2 to form the highly emissive 10-methyl-9-acridone, [139,143] as displayed in Scheme 2A.S of ar, alkaline conditions were required for the CL emission of acridinium esters.H owever,r ecently,a cridinium ester derivatives were synthesized which allow the CL reaction to proceed under neutral conditions.T his was achieved by introducing electron withdrawing groups (e.g.…”

“…However, the challenge to gain higher CL quantum yields, tune the emission range, or simplify the CL system is to modify the reaction environment or the luminophore itself in such a way that the CL properties are not diminished accidentally. Nevertheless, recent research into common luminophores, such as dioxetanes,[ 131 , 132 ] peroxyoxalates (POs),[ 122 , 133 , 134 , 135 , 136 , 137 ] acridinium esters,[ 138 , 139 , 140 , 141 ] luminol,[ 129 , 142 ] and their respective derivatives, led to the development of a plethora of advanced, promising self‐reporting CL systems. The CL of acridinium esters, for example, can be triggered by antioxidants, enzymes or peroxides and thus finds application in (biomedical) analytics as self‐reporting sensor for these substances.…”

Vorbeugen oder Heilen – die beispiellose Notwendigkeit von selbstberichtenden Materialien

“…Die Herausforderung,h çhere CL-Quantenausbeuten zu erzielen, den Emissionsbereich einzustellen oder das CL-System zu vereinfachen, besteht jedoch darin, die Reaktionsumgebung oder den Luminophor selbst so zu modifizieren, dass die CL-Eigenschaften nicht versehentlich vermindert werden. Nichtsdestotrotz führte die aktuelle Forschung an bekannten Luminophoren wie Dioxetanen, [131,132] Peroxyoxalaten (POs), [122,[133][134][135][136][137] Acridiniumestern, [138][139][140][141] Luminol [129,142] und deren jeweiligen Derivaten zur Entwicklung einer Fülle an fortschrittlichen, vielversprechenden selbstberichtenden CL-Systemen. Die CL von Acridiniumestern beispielsweise kann durch Antioxidantien, Enzyme oder Peroxide ausgelçst werden und findet daher in der (biomedizinischen) Analytik als selbstberichtender Sensor fürd iese Stoffe Anwendung.…”

Enhanced chemiluminescence of the fluorescein–KIO4 system by CdTe quantum dots for determination of catechol

“…Conventional CL reagents such as luminol, lucigenin, tris(2,2‐bipyridyl)ruthenium‐(II), peroxyoxalate have been extensively developed . Nevertheless, they are relatively high‐cost.…”