We present pressure profiles of galaxy clusters determined from high-resolution Sunyaev-Zel'dovich (SZ) effect observations of 14 clusters, which span the redshift range of z 0.25 0.89 < <. The procedure simultaneously fits spherical cluster models to MUSTANG and Bolocam data. In this analysis, we adopt the generalized NFW parameterization of pressure profiles to produce our models. Our constraints on ensemble-average pressure profile parameters, in this study γ, C 500 , and P 0 , are consistent with those in previous studies, but for individual clusters we find discrepancies with the X-ray derived pressure profiles from the ACCEPT2 database. We investigate potential sources of these discrepancies, especially cluster geometry, electron temperature of the intracluster medium, and substructure. We find that the ensemble mean profile for all clusters in our sample is described by the parameters C P , , 0.3 , 1.3 , 8.6 500 0 0