Hydrogel Contact Lenses Surface Roughness and Bacterial Adhesion

Giráldez, María Jesús; Yebra‐Pimentel, Eva

doi:10.5772/48436

Cited by 5 publications

(1 citation statement)

References 121 publications

(177 reference statements)

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“…Surface roughness is a crucial geometrical parameter of surface characteristics, which is in direct contact with surrounding live organisms, and has a biological influence on the bacterial adhesion manner [96]. Higher surface roughness would increase the available active contact area for thermodynamic reactions, and surface irregularities like peaks and troughs serve as shelters for bacteria to promote the survival rate and avoid meeting unfavorable environmental factors [102].…”

Section: Predisposing Factors Of Scl-induced Biofoulingmentioning

confidence: 99%

Biomimetic Functional Surfaces towards Bactericidal Soft Contact Lenses

Mao

2020

Micromachines

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The surface with high-aspect-ratio nanostructure is observed to possess the bactericidal properties, where the physical interaction between high-aspect-ratio nanostructure could exert sufficient pressure on the cell membrane eventually lead to cell lysis. Recent studies in the interaction mechanism and reverse engineering have transferred the bactericidal capability to artificial surface, but the biomimetic surfaces mimicking the topographical patterns on natural resources possess different geometrical parameters and surface properties. The review attempts to highlight the recent progress in bactericidal nanostructured surfaces to analyze the prominent influence factors and cell rupture mechanism. A holistic approach was utilized, integrating interaction mechanisms, material characterization, and fabrication techniques to establish inclusive insights into the topographical effect and mechano-bactericidal applications. The experimental work presented in the hydrogel material field provides support for the feasibility of potentially broadening applications in soft contact lenses.

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Section: Predisposing Factors Of Scl-induced Biofoulingmentioning

confidence: 99%

Biomimetic Functional Surfaces towards Bactericidal Soft Contact Lenses

Mao

2020

Micromachines

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Topographic characterization of unworn contact lenses assessed by atomic force microscopy and wavelet transform

Ţălu

Stępień

Çağlayan

2015

Microscopy Res & Technique

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This paper analyses the three-dimensional (3-D) surface morphology of optic surface of unworn contact lenses (CLs) using atomic force microscopy (AFM) and wavelet transform. Refractive powers of all lens samples were 2.50 diopters. Topographic images were acquired in contact mode in air-conditioned medium (35% RH, 23°C). Topographic measurements were taken over a 5 µm × 5 µm area with 512 pixel resolution. Resonance frequency of the tip was 65 kHz. The 3-D surface morphology of CL unworn samples revealed (3-D) micro-textured surfaces that can be analyzed using (AFM) and wavelet transform. AFM and wavelet transform are accurate and sensitive tools that may assist CL manufacturers in developing CLs with optimal surface characteristics.

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