2022
DOI: 10.3389/fnut.2022.1006520
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Hydrogels as promising carriers for the delivery of food bioactive ingredients

Abstract: The burden of public health challenges associated with the western dietary and living style is growing. Nutraceuticals have been paid increasing attentions due to their effects in promotion of health. However, in the gastrointestinal (GI) tract, the nutraceuticals suffer from not only the harsh acidic environment of the stomach and a variety of digestive enzymes, but also the antibacterial activity of intestinal bile salts and the action of protease from the gut microbiota. The amount of the nutraceuticals arr… Show more

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Cited by 9 publications
(4 citation statements)
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“…By controlling factors such as pH, temperature, and polymer concentration, one can achieve the desired properties in physically crosslinked hydrogels [21]. Various physical crosslinking methods have been developed, including processes such as heating/cooling, freeze-thaw cycles, and complex coacervation, for the preparation of natural polymer-based hydrogels [22]. A diagram of the emulsion-based encapsulation method is shown in Figure 1.…”
Section: Emulsion-based Encapsulation and Hydrogelsmentioning
confidence: 99%
“…By controlling factors such as pH, temperature, and polymer concentration, one can achieve the desired properties in physically crosslinked hydrogels [21]. Various physical crosslinking methods have been developed, including processes such as heating/cooling, freeze-thaw cycles, and complex coacervation, for the preparation of natural polymer-based hydrogels [22]. A diagram of the emulsion-based encapsulation method is shown in Figure 1.…”
Section: Emulsion-based Encapsulation and Hydrogelsmentioning
confidence: 99%
“…The degree of swelling is an important property of a food hydrogel to determine the release pro le of the nutraceuticals or bioactive compounds contained in the hydrogel (Li et al 2022). Hydrogel samples that had been dried in the oven were then weighed and immersed in PBS solution, with measurement times of 0, 3, 6, 9, 12, 24, and 48 hours.…”
Section: Degree Of Swelling and Weight Lossmentioning
confidence: 99%
“…Synthesis of composite hydrogel based on starch (polysaccharide) is an effort to reduce the negative impact on the environment and improve starch utilization as a functional food. Some studies have demonstrated that the design of natural-based hydrogel is crucial in contemporary food products, such as extending shelf life, improving sensory texture, and more bioavailable bioactive components (Li et al 2022).…”
Section: Introductionmentioning
confidence: 99%
“…An additional benefit is that degradation products are recognized and further metabolized by the body. They present desirable characteristics for biomaterial design, such as low toxicity, biocompatibility, biodegradability, and availability, which are essential for biomedical-and Gels 2023, 9, 376 2 of 48 therapeutic-related applications [11][12][13][14][15]. Hydrogels that include synthetic compounds present the advantages of control over the synthesis processes, definite molecular weights and chemical structures, and good mechanical properties.…”
Section: Introductionmentioning
confidence: 99%