Hydrogen bonding in aromatic formamides

4-Acetamidobenzenesulfonyl azide

“…2 and Table 2). The hydrogen bonds observed here are in the usual range for strong amideto-amide hydrogen bonds, and, as is often observed for amides and formamides and other related systems, the ability to form strong hydrogen bonds is the determining factor behind the type of packing realised in the solid state (Zeller et al, 2005). For p-ABSA, the hydrogen bonds connect all three molecules, forming an infinite chain arranged in a helix-like fashion around the direction of the b axis of the unit cell (Fig.…”

The influence of substitution and weak interactions on the crystal structures of a series of 2,6-disubstituted N-arylthioamides

“…5 This may be due to the smaller size of the oxygen atom compared to the sulfur atom of the compounds in this study. All five molecules have two planes defined by the phenyl ring [C(1)-C( 6)] and the thioamide moiety [C(1)-N(1)-C(7)]S (1)]. The dihedral angle between these two planes ranges between 51.8(2) and 62.6(2) for the five compounds (see Table 3).…”

“…Amides and particularly formamides and thioamides are known to be of fundamental chemical and biological interest as some of the features of these compounds can be manipulated to obtain certain distinct and useful physical and chemical properties. 1,2 As such, these compounds can be used to model their more complex parent biomacromolecules that contain the formamide or thioamide functional groups. Formamides and thioamides themselves are versatile compounds that have found a wide range of applications in academia, industry and biological systems.…”

Formation of isostructural solid solutions in 2,6-disubstitutedN-phenylformamides andN-phenylthioamides

“…In recent years studies involving the amide group and its relevance to biological and chemical systems have been carried out by several researchers. Amides and particularly formamides and thioamides have been known to be of fundamental chemical (polymorphism and crystal engineering) and biological interest (protein folding) as some of the features of these compounds can be manipulated to obtain useful physical and chemical properties (Zeller et al, 2005;Tan et al, 2006).…”

“…Structural mimicry and co-crystallization continues to gain significance for its application to the design of new supramolecular structures with desired functional properties (Trask et al, 2004). This has been an effective method, notably in the field of pharmaceuticals, to alter physical properties like solubility (or bioavailability), stability and the melting point of the compounds (Remenar et al, 2003;Walsh et al, 2003;Oswald et al, 2002), and finally in materials with optoelectronic properties, to alter their conductivity, charge transfer and magnetism in nonporous materials (Zeller et al, 2005).…”