Human activities mostly impact the trend and direction of rainwater, groundwater, and other river basin resources in the watershed in Africa. These activities alter river flows and the quality of usable water supplies at both highlands and lowlands. A watershed is indeed a conserved area of land that collects rain, sleet and snow, and empties or penetrates groundwater sources. The act of managing the activities around the watershed is integrated watershed management, which considers the social, economic, and environmental issues in tandem with the human, institutional, natural, and sustainability systems, which are the key drivers as identified in this study, as well as community interests and participation, to manage groundwater resources sustainably. These watersheds, river basins, and groundwater resources provide important services for communities and biodiversity. This paper reveals that the best way to protect groundwater resources is on a watershed basis using sustainable management measures. This technique enables us to handle a variety of concerns and objectives while also allowing us to plan in a complicated and uncertain environment. Sustaining a regional and sub-regional watershed involves cooperation and participation from a wide range of community interests and water users, including municipalities, companies, people, agencies, and landowners, for stakeholders’ input to be successful. All of the strategies and plans are produced with regard to one another, as well as the overall conditions of the watershed, local land uses, and specific regional transboundary issues.