Hydronephrosis in patients with cervical cancer is an indicator of poor outcome

Yang, You-Rong; Chen, Szu‐Ju; Yen, Pin-Yeh; Huang, Chi‐Ping; Chiu, Lu-Ting; Lin, Wu-Chou; Chen, Huey‐Yi; Chen, Yung‐Hsiang; Chen, Wen‐Chi

doi:10.1097/md.0000000000024182

Cited by 8 publications

(5 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In addition, treatment delays, comorbidities, and more advanced cervical cancer can increase the mortality of patients with hydronephrosis. 11,12 In this study, it was also found that patients who underwent deobstruction had a higher survival rate. Previous studies also reported that the 1-year survival of patients who underwent deobstruction was higher J Indon Med Assoc, Volum: 74, Nomor: 2, April -Mei 2024 than those who did not.…”

Section: Discussionsupporting

confidence: 56%

Prevalence and Survival Rate of Advanced Stage Cervical Cancer Patients with Obstructive Uropathy in a Tertiary Hospital

Daryanto,

Nurseta,

Wisnu

2024

J Indon Med Assoc

View full text Add to dashboard Cite

Introduction: This study aims to determine the prevalence and survival rate of advanced cervical cancer patients with obstructive uropathy based on grade of hydronephrosis, type of hydronephrosis, deobstruction action, type of deobstruction, clinical stage, and cancer cell type.Method: This research is a descriptive analytical study with a cross-sectional retrospective approach. Samples were obtained from medical records of patients with stage IIIB, IVA and IVB cervical cancer who were treated at RSUD Dr. Saiful Anwar Malang in 2016–2023. Sampling was carried out using the total sampling method.Result: Of the 171 patients, the majority of patients had stage IIIB cervical cancer (71.9%), moderate (72.5%) and bilateral (90.1%) hydronephrosis were found in the majority of patients. SCC dominated the sample (82.5%) and was followed by ADC (14.6%). Most patients underwent deobstruction (64.3%) with DJ stent insertion being the most common type of deobstruction (84.5%). Patients with stage IVB have a lower survival rate than IIIB and IVA (p>0.05). Patients with SCC had lower survival (3%) than ADC (5%). The average survival rate for the three grades of hydronephrosis was not significantly different (p>0.05). Patients undergoing deobstruction showed a higher survival rate (5%) (p<0.05). DJ stent, PCN, and UCS insertion showed similar survival rates in patients (p>0.05).Conclusion: Stage IIIB cervical cancer, moderate hydronephrosis, bilateral hydronephrosis, and SCC dominated the patients in the study. Patients with stage IVB cervical cancer, SCC, unilateral or severe hydronephrosis have a worse prognosis. The presence of deobstruction indicates a better prognosis and can be performed with PCN, DJ stent insertion, or UCS.

show abstract

Section: Discussionsupporting

confidence: 56%

Prevalence and Survival Rate of Advanced Stage Cervical Cancer Patients with Obstructive Uropathy in a Tertiary Hospital

Daryanto,

Nurseta,

Wisnu

2024

J Indon Med Assoc

View full text Add to dashboard Cite

show abstract

“…It occurs as a consequence of a tumor or lymph nodes growth, inflammation or fibrosis in pelvis, which results in pain occurrence, infection, or renal malfunction due to obstruction. Furthermore, it is considered to be an indicator of a bad prognosis in such patients [9].…”

Section: Discussionmentioning

confidence: 99%

A misplacement of a ureteral stent into the abdominal aorta: a case report of a rare retrograde ureteral stenting complication

Prijovic¹,

Cegar

Cvetić

et al. 2022

BMC Women's Health

View full text Add to dashboard Cite

Background Cervical cancer is often associated with malignant ureteral obstruction and consequent hydronephrosis. Hydronephrosis caused in this way can be resolved by placing ureteral stents or performing a percutaneous nephrostomy. Complications that may occur during the retrograde ureteral stent placement are usually mild, but serious complications such as stent migration into the cardiovascular system are also possible. Here we present an unusual case where a ureteral stent entered the abdominal aorta during the cystoscopic ureteral stenting, which was resolved by a cystoscopic stent removal kept in check by endovascular catheters. Case presentations The 48-year-old female patient was treated in the regional secondary healthcare facility due to bilateral hydronephrosis caused by cervical cancer. The patient had bilateral percutaneous nephrostomies and ureteral stents. Due to the calcification of the left ureteral stent, an urethrorenoscopy with lithotripsy of the calculus in the left ureter was performed in the regional secondary healthcare facility, and the ureteral stent was cystoscopically replaced. The control radiography of the urinary tract showed a misplacement of the left ureteral stent, and a computed tomography showed that the stent was located in the abdominal aorta. The patient was referred to the University Clinical Center of Serbia, where a ureteral stent was cystoscopically removed from the abdominal aorta under the control of endovascular catheters. The patient was in good general condition at all times, with no signs of bleeding, and she was discharged from the hospital on the fourth postoperative day. Conclusions The migration of a ureteral stent into the abdominal aorta and the cardiovascular system in general is a rare type of ureteral stenting complication whose treatment requires a multidisciplinary approach. In order to prevent such complications, it is necessary to strictly adhere to the indications for the ureteral stent placement in the case of malignant ureteral obstruction. Also, this procedure should be performed according to the current guidelines and controlled by an X-ray or ultrasound.

show abstract

“…Diabetes is a significant prognostic factor in cervical cancer patients and is associated with a poor prognosis, according to a meta-analysis by Chen et al, (2017). The fact that the hydronephrosis group had a high all-cause mortality rate may be due to the coexistence of many comorbidities (Yang et al, 2021).…”

Section: Author Contribution Statementmentioning

confidence: 99%

Survival Outcome of Urinary Diversion in Advanced Cervical Cancer Patients with Hydronephrosis

Dhani,

Daryanto,

Seputra

2023

Asian Pac J Cancer Prev

View full text Add to dashboard Cite

Objective: Urinary diversion is the treatment of choice for cervical cancer patients with urinary tract obstruction. The aim of this study is to determine the survival rate among advanced cervical cancer patients with hydronephrosis who undergo urinary diversion and factors that affect patient survival. Methods: Clinical data of cervical cancer patients with International Federation of Gynecology and Obstetrics (FIGO) Stage-IIIB or advanced cervical cancer were not surgical candidates admitted to Saiful Anwar Hospital, Malang from May 2016 to August 2022 were retrospectively analyzed. The parameters including age, cancer stage, comorbidity, cancer treatment at diagnosis, hydronephrosis treatment, grade, site, and survival, were analyzed using the IBM SPSS Statistics version 21. The significance level was set up to 0.05. Result: One hundred eighteen patients were included in this study. Most patients were under 60 (84.75%) and presented with stage IIIB (79.66%). Diabetes mellitus type 2 (8.47%), hypertension (7.63%), acute kidney injury (16.10%), and chronic kidney disease (36.78%) were comorbidities discovered in patients. More than half of patients received chemotherapy (54.24%). Ureteral stents were inserted in 85.59% of patients. Patients with moderate hydronephrosis were the most common, accounting for 67.80% of all cases. Patients with bilateral hydronephrosis outnumber those with unilateral by 91.53% to 8.47%. The survival rate did not differ significantly between ureteral stents (median survival was 11.00 months) and percutaneous nephrostomies (median survival was 15.00 months), p=0.749. In univariate analysis, age, cancer stage, and hydronephrosis stage were associated with worse 1-year survival. In multivariate analysis, age, DM type 2, cancer staging and hydronephrosis staging were associated with worse 1-year survival. Conclusion: In advanced cervical cancer patients, urinary diversion techniques such as ureteral stents and percutaneous nephrostomy offer similar survival rates. In addition, age, cancer stage, DM type 2, and hydronephrosis site are strong predictors of a worsening survival rate in patients.

show abstract

Hydronephrosis in patients with cervical cancer is an indicator of poor outcome

Cited by 8 publications

References 29 publications

Prevalence and Survival Rate of Advanced Stage Cervical Cancer Patients with Obstructive Uropathy in a Tertiary Hospital

Prevalence and Survival Rate of Advanced Stage Cervical Cancer Patients with Obstructive Uropathy in a Tertiary Hospital

A misplacement of a ureteral stent into the abdominal aorta: a case report of a rare retrograde ureteral stenting complication

Survival Outcome of Urinary Diversion in Advanced Cervical Cancer Patients with Hydronephrosis

Contact Info

Product

Resources

About